SCHEMBL25758670

SCHEMBL25758670

CCCCCCCCC(CCCCCC)C(=O)OCCCCCC1(CCCCCOC(=O)C(CCCCCC)CCCCCCCC)CCCN1CCCC

nearest known ligand 0.38

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.37
MAPK1 P28482 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
GRIK1 P39086 2/20 0.35
GRIK2 Q13002 2/20 0.35
PRKCD Q05655 2/20 0.34
NAAA Q02083 1/20 0.33
NOD1 Q9Y239 2/20 0.33
SLC1A2 P43004 1/20 0.33
SLC1A1 P43005 1/20 0.33
HCAR2 Q8TDS4 1/20 0.33
THRA P10827 2/20 0.32
THRB P10828 2/20 0.32
EPHX1 P07099 1/20 0.32
CA2 P00918 1/20 0.32
GBA2 Q9HCG7 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25758816 0.97 MAPT (0.39) MAPTMAPK1NPSR1L3MBTL1GRIK1
SCHEMBL25757485 0.93 MAPT (0.34) MAPTMAPK1NPSR1L3MBTL1GRIK1
SCHEMBL25761358 0.92 CPB2 (0.38) MAPTMAPK1NPSR1L3MBTL1GRIK1
SCHEMBL25761405 0.92 MAPT (0.35) MAPTMAPK1NPSR1L3MBTL1GRIK1
SCHEMBL25757497 0.90 MAPT (0.36) MAPTMAPK1NPSR1L3MBTL1GRIK1
SCHEMBL25757701 0.86 MAPT (0.33) MAPTMAPK1NPSR1L3MBTL1PRKCD
SCHEMBL25760729 0.82 ALDH1A1 (0.43) MAPTMAPK1L3MBTL1PRKCDNOD1
SCHEMBL25760423 0.81 S1PR5 (0.38) MAPTMAPK1NPSR1L3MBTL1PRKCD
SCHEMBL23223398 0.75 NAAA (0.55) MAPTNPSR1GRIK1GRIK2NAAA
SCHEMBL23136949 0.75 NAAA (0.55) MAPTNPSR1GRIK1GRIK2NAAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230202977-A1 CYCLIC LIPIDS AND METHODS OF USE THEREOF RENAGADE THERAPEUTICS MANAGEMENT INC. 2023-06-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230202977-A1 CYCLIC LIPIDS AND METHODS OF USE THEREOF SGMS1, SGMS2, LNPEP MAPT 4102/4885MAPK1 4510/4885NPSR1 2262/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.