Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 1/20 | 0.38 |
| ▸ | IDH1 | O75874 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALKBH3 | Q96Q83 | 2/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | MAT2A | P31153 | 1/20 | 0.34 |
| ▸ | CSF1R | P07333 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21751336 | 0.94 | ADORA3 (0.41) | CASRADORA3ADORA2AADORA1ALDH1A1 | |
| SCHEMBL25760179 | 0.94 | CASR (0.39) | CASRIDH1ADORA3ADORA2AADORA1 | |
| SCHEMBL21751454 | 0.93 | ADORA3 (0.39) | CASRADORA3ADORA2AADORA1ALDH1A1 | |
| SCHEMBL30800148 | 0.93 | ADORA3 (0.39) | CASRADORA3ADORA2AADORA1ALDH1A1 | |
| SCHEMBL21751359 | 0.91 | ADORA3 (0.37) | CASRADORA3ADORA2AADORA1ALDH1A1 | |
| SCHEMBL25760164 | 0.91 | ADORA3 (0.37) | CASRADORA3ADORA2AADORA1ALDH1A1 | |
| SCHEMBL17407642 | 0.90 | ALKBH3 (0.38) | ALDH1A1ALKBH3MMP9MAOAMAOB | |
| SCHEMBL21751461 | 0.90 | KDM4E (0.41) | ADORA3ALDH1A1GAAMEN1KMT2A | |
| SCHEMBL10196888 | 0.89 | ABCB1 (0.39) | ADORA3ADORA1ALDH1A1ALKBH3MMP9 | |
| SCHEMBL20841761 | 0.89 | ABCB1 (0.39) | ADORA3ADORA1ALDH1A1ALKBH3MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11691976-B2 | Coelenterazine analogues | PROMEGA CORPORATION (US) | 2023-07-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11691976-B2 | Coelenterazine analogues | GLB1, SI, TCF7L2 | CASR 2864/4885IDH1 3282/4885ADORA3 3089/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.