Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | CASR | P41180 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.34 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | CDK4 | P11802 | 1/20 | 0.34 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.34 |
| ▸ | CCND1 | P24385 | 1/20 | 0.34 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 4/20 | 0.34 |
| ▸ | PARP1 | P09874 | 2/20 | 0.34 |
| ▸ | CSF1R | P07333 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21751336 | 0.94 | ADORA3 (0.41) | ADORA3ADORA2AADORA1CASRALDH1A1 | |
| SCHEMBL25760179 | 0.92 | CASR (0.39) | ADORA3ADORA2AADORA1CASRALDH1A1 | |
| SCHEMBL30800148 | 0.91 | ADORA3 (0.39) | ADORA3ADORA2AADORA1CASRALDH1A1 | |
| SCHEMBL21751454 | 0.91 | ADORA3 (0.39) | ADORA3ADORA2AADORA1CASRALDH1A1 | |
| SCHEMBL19206714 | 0.91 | ALDH1A1 (0.38) | ADORA3ADORA2AADORA1CASRALDH1A1 | |
| SCHEMBL21751340 | 0.91 | ADORA3 (0.36) | ADORA3ADORA2AADORA1CASRALDH1A1 | |
| SCHEMBL25760174 | 0.91 | CASR (0.38) | ADORA3ADORA2AADORA1CASRALDH1A1 | |
| SCHEMBL25760166 | 0.90 | THRB (0.38) | ALDH1A1PDE3BPDE3ACCNE2CCNE1 | |
| SCHEMBL21751401 | 0.89 | LTB4R (0.43) | ALDH1A1ALOX5 | |
| SCHEMBL21751359 | 0.89 | ADORA3 (0.37) | ADORA3ADORA2AADORA1CASRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11691976-B2 | Coelenterazine analogues | PROMEGA CORPORATION (US) | 2023-07-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11691976-B2 | Coelenterazine analogues | GLB1, SI, TCF7L2 | ADORA3 3089/4885ADORA2A 1970/4885ADORA1 4310/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.