Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 7/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | TSHR | P16473 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | CASP1 | P29466 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | USP2 | O75604 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CASP7 | P55210 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | ALKBH3 | Q96Q83 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28396528 | 0.94 | ADORA2B (0.39) | ADORA2BADORA2AALDH1A1TSHRKDM4E | |
| SCHEMBL21751453 | 0.90 | ADORA2A (0.33) | ADORA2BADORA2AALDH1A1TSHRKDM4E | |
| SCHEMBL25760270 | 0.89 | ADORA2B (0.38) | ADORA2BADORA2AALDH1A1TSHRKDM4E | |
| SCHEMBL28888591 | 0.88 | PSD (0.38) | ADORA2BADORA2AALDH1A1TSHRKDM4E | |
| SCHEMBL21751428 | 0.86 | ADORA2A (0.32) | ADORA2BADORA2AALDH1A1TSHRKDM4E | |
| SCHEMBL30800177 | 0.86 | ADORA2A (0.32) | ADORA2BADORA2AALDH1A1TSHRKDM4E | |
| SCHEMBL25760371 | 0.86 | ADORA2B (0.37) | ADORA2BADORA2AALDH1A1TSHRKDM4E | |
| SCHEMBL2670126 | 0.86 | ALDH1A1 (0.39) | ADORA2BADORA2AALDH1A1TSHRKDM4E | |
| SCHEMBL19810310 | 0.85 | ADORA2B (0.38) | ADORA2BADORA2AALDH1A1TSHRKDM4E | |
| SCHEMBL25760317 | 0.84 | NPSR1 (0.38) | ADORA2BADORA2AALDH1A1TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11691976-B2 | Coelenterazine analogues | PROMEGA CORPORATION (US) | 2023-07-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11691976-B2 | Coelenterazine analogues | GLB1, SI, TCF7L2 | ADORA2B 3105/4885ADORA2A 1970/4885ALDH1A1 3541/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.