Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSD | A5PKW4 | 3/20 | 0.38 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19810310 | 0.93 | ADORA2B (0.38) | ALKBH3ADORA2AADORA2BKMT2AALDH1A1 | |
| SCHEMBL2670126 | 0.93 | ALDH1A1 (0.39) | ADORA2AADORA2BKMT2AALDH1A1MEN1 | |
| SCHEMBL19810212 | 0.91 | ALDH1A1 (0.38) | ADORA2AADORA2BKMT2AALDH1A1MEN1 | |
| SCHEMBL5560844 | 0.91 | ALDH1A1 (0.37) | ADORA2AADORA2BKMT2AALDH1A1NPSR1 | |
| SCHEMBL28391210 | 0.91 | PRNP (0.36) | ADORA2AADORA2BKMT2AALDH1A1MEN1 | |
| SCHEMBL19810320 | 0.91 | LTB4R (0.36) | ADORA2AADORA2BKMT2AALDH1A1MEN1 | |
| SCHEMBL28394541 | 0.90 | ADORA2B (0.35) | ADORA2AADORA2BKMT2AALDH1A1MEN1 | |
| SCHEMBL25781925 | 0.90 | ADORA2B (0.35) | ADORA2AADORA2BKMT2AALDH1A1MEN1 | |
| SCHEMBL20211769 | 0.89 | TSHR (0.36) | ADORA2AADORA2BKMT2AALDH1A1MEN1 | |
| SCHEMBL21751352 | 0.88 | BRAF (0.34) | ADORA2AADORA2BKMT2AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111116594-B | C-6 modified NanoLuc analogue and preparation method and application thereof | 山东大学 | 2021-05-28 | — | — | CN | disclosed |
| CN-111116594-A | C-6 modified NanoLuc analogue and preparation method and application thereof | 山东大学 | 2020-05-08 | — | — | CN | disclosed |