Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.35 |
| ▸ | KDM4A | O75164 | 1/20 | 0.35 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.35 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.35 |
| ▸ | GABRP | O00591 | 2/20 | 0.34 |
| ▸ | GABRD | O14764 | 2/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.34 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.34 |
| ▸ | GABRE | P78334 | 2/20 | 0.34 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.34 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.34 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24458184 | 0.85 | CA1 (0.44) | CA1KDM4CKDM4APHF8KDM2A | |
| SCHEMBL19506126 | 0.83 | GAA (0.35) | CA1KDM4CKDM4APHF8KDM2A | |
| SCHEMBL25762207 | 0.82 | CA1 (0.37) | CA1KDM4CKDM4APHF8KDM2A | |
| SCHEMBL4320985 | 0.82 | ALDH1A1 (0.38) | CA1KDM4CKDM4APHF8KDM2A | |
| SCHEMBL21288117 | 0.77 | KDM4C (0.51) | KDM4CKDM4APHF8KDM2AGABRP | |
| SCHEMBL12197973 | 0.77 | ALDH1A1 (0.40) | CA1KDM4CKDM4APHF8KDM2A | |
| SCHEMBL3188866 | 0.77 | ACHE (0.40) | KDM4CPHF8KDM2ANPC1RAB9A | |
| SCHEMBL12156637 | 0.77 | ALDH1A1 (0.35) | CA1KDM4CKDM4APHF8KDM2A | |
| SCHEMBL17177762 | 0.77 | CNR1 (0.45) | PHF8KDM2ACHRNB2CHRNB4CHRNA4 | |
| SCHEMBL12629214 | 0.77 | CYP1A2 (0.39) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023215740-A1 | IMMUNOMODULATORY ANTIBODY-DRUG CONJUGATES | SEAGEN INC. (US) | 2023-11-09 | — | — | WO | disclosed |