Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | KDM4A | O75164 | 1/20 | 0.36 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.36 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | GABRP | O00591 | 2/20 | 0.31 |
| ▸ | GABRD | O14764 | 2/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.31 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24458184 | 0.87 | CA1 (0.44) | ALDH1A1CA1KDM4CCHRNB2CHRNB4 | |
| SCHEMBL25762207 | 0.83 | CA1 (0.37) | ALDH1A1CA1KDM4CCHRNB2CHRNB4 | |
| SCHEMBL23732049 | 0.83 | CA1 (0.37) | CA1KDM4CCHRNB2CHRNB4CHRNA4 | |
| SCHEMBL26742525 | 0.82 | CA1 (0.35) | ALDH1A1CA1KDM4CCHRNB2CHRNB4 | |
| SCHEMBL3677205 | 0.80 | CNR1 (0.49) | ALDH1A1CHRNB2CHRNB4CHRNA4CHRNA3 | |
| SCHEMBL21288117 | 0.79 | KDM4C (0.51) | KDM4CCHRNB2CHRNB4CHRNA4KDM4A | |
| SCHEMBL12197973 | 0.78 | ALDH1A1 (0.40) | ALDH1A1CA1KDM4CCHRNB2CHRNB4 | |
| SCHEMBL12156637 | 0.78 | ALDH1A1 (0.35) | ALDH1A1CA1KDM4CCHRNB2CHRNB4 | |
| SCHEMBL1984444 | 0.77 | KDM4C (0.54) | KDM4CCHRNB2CHRNB4CHRNA4CHRNA3 | |
| SCHEMBL22564647 | 0.77 | EPHX2 (0.53) | ALDH1A1KDM4CKDM4APHF8KDM2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009147221-A1 | SMALL MOLECULE LEPTIN RECEPTOR MODULATORS | BIOVITRUM AB (PUBL) (SE) | 2009-12-10 | — | — | WO | claimed |
| WO-2009147221-A1 | SMALL MOLECULE LEPTIN RECEPTOR MODULATORS | BIOVITRUM AB (PUBL) (SE) | 2009-12-10 | — | — | WO | disclosed |