Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 7/20 | 0.51 |
| ▸ | KDM4A | O75164 | 6/20 | 0.51 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.51 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.46 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.41 |
| ▸ | GABRP | O00591 | 2/20 | 0.41 |
| ▸ | GABRD | O14764 | 2/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.41 |
| ▸ | GABRE | P78334 | 2/20 | 0.41 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.41 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21288119 | 0.84 | EPHX2 (0.47) | KDM4CKDM4APHF8KDM2AEPHX2 | |
| SCHEMBL23188553 | 0.83 | EPHX2 (0.46) | KDM4CKDM4APHF8KDM2AEPHX2 | |
| SCHEMBL3998131 | 0.82 | KDM4C (0.71) | KDM4CKDM4APHF8KDM2AEPHX2 | |
| SCHEMBL24458184 | 0.82 | CA1 (0.44) | KDM4CKDM4APHF8KDM2AEPHX2 | |
| SCHEMBL26211951 | 0.81 | KDM4C (0.50) | KDM4CKDM4APHF8KDM2AEPHX2 | |
| SCHEMBL22564647 | 0.80 | EPHX2 (0.53) | KDM4CKDM4APHF8KDM2AEPHX2 | |
| SCHEMBL21288011 | 0.79 | EPHX2 (0.50) | KDM4CKDM4APHF8KDM2AEPHX2 | |
| SCHEMBL25762207 | 0.79 | CA1 (0.37) | KDM4CKDM4APHF8KDM2AEPHX2 | |
| SCHEMBL13133254 | 0.79 | EPHX2 (0.58) | KDM4CEPHX2SLC22A6KDM5AFFAR4 | |
| SCHEMBL4320985 | 0.79 | ALDH1A1 (0.38) | KDM4CKDM4APHF8KDM2AGABRP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11787764-B2 | Heptamethine cyanines for use as fluorescent markers of the biliary and renal systems | CHILDREN'S NATIONAL MEDICAL CENTER (US) | 2023-10-17 | — | — | US | disclosed |
| US-20210100919-A1 | HEPTAMETHINE CYANINES FOR USE AS FLUORESCENT MARKERS OF THE BILIARY AND RENAL SYSTEMS | CHILDREN'S NATIONAL MEDICAL CENTER (US) | 2021-04-08 | — | — | US | disclosed |
| WO-2019161091-A9 | HEPTAMETHINE CYANINES FOR USE AS FLUORESCENT MARKERS OF THE BILIARY AND RENAL SYSTEMS | CHILDREN'S NATIONAL MEDICAL CENTER (US) | 2019-10-24 | — | — | WO | disclosed |
| WO-2019161091-A1 | HEPTAMETHINE CYANINES FOR USE AS FLUORESCENT MARKERS OF THE BILIARY AND RENAL SYSTEMS | CHILDREN'S NATIONAL MEDICAL CENTER (US) | 2019-08-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11787764-B2 | Heptamethine cyanines for use as fluorescent markers of the biliary and renal systems | CD68, PAX2, PYGL | KDM4C 2782/4885KDM4A 2998/4885PHF8 3060/4885 |
| US-20210100919-A1 | HEPTAMETHINE CYANINES FOR USE AS FLUORESCENT MARKERS OF THE BILIARY AND RENAL SYSTEMS | CD68, PAX2, PYGL | KDM4C 2782/4885KDM4A 2998/4885PHF8 3060/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.