Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.53 |
| ▸ | AR | P10275 | 1/20 | 0.53 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.48 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.48 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.46 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.45 |
| ▸ | FYN | P06241 | 3/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SYK | P43405 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25763769 | 0.88 | KCNH2 (0.48) | PGRARDYRK1ANR1H2NR1H3 | |
| SCHEMBL25763766 | 0.85 | CYP11B2 (0.52) | PDGFRBPDGFRACYP11B2FYNALDH1A1 | |
| SCHEMBL25764075 | 0.83 | AR (0.49) | ARCYP11B2ALDH1A1GAAHPGD | |
| SCHEMBL25764079 | 0.83 | ESR1 (0.39) | ARAKR1C3AKR1C2CYP11B2NPC1 | |
| SCHEMBL25764072 | 0.82 | MAP4K4 (0.40) | PGRCYP11B2KDM4EALDH1A1GLA | |
| SCHEMBL25764706 | 0.82 | PDGFRB (0.51) | PDGFRBPDGFRAAKR1C3AKR1C2CA12 | |
| SCHEMBL25763772 | 0.80 | FYN (0.43) | CYP11B2FYNALDH1A1GAASYK | |
| SCHEMBL25763798 | 0.80 | KDM1A (0.39) | PGRARCYP11B1CYP11B2NR1H2 | |
| SCHEMBL4012188 | 0.76 | NR1H2 (0.63) | NR1H2NR1H3 | |
| SCHEMBL24453555 | 0.73 | CLK4 (0.50) | PDGFRBPDGFRACA12CA9CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023116835-A1 | MULTI-PROTEIN DEGRADATION AGENT HAVING IMIDE SKELETON | 苏州开拓药业股份有限公司 | 2023-06-29 | — | — | WO | disclosed |