Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 4/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25763766 | 0.86 | CYP11B2 (0.52) | NR1H3NR1H2CYP11B2 | |
| SCHEMBL25764075 | 0.85 | AR (0.49) | NR1H3HSD11B1NR1H2ARCYP11B2 | |
| SCHEMBL25764072 | 0.84 | MAP4K4 (0.40) | NR1H3PIK3CDNR1H2MAPTCYP11B2 | |
| SCHEMBL25763768 | 0.83 | PGR (0.53) | NR1H3NR1H2ARAKR1C3AKR1C2 | |
| SCHEMBL25763772 | 0.82 | FYN (0.43) | NR1H3NR1H2CYP11B2 | |
| SCHEMBL25763769 | 0.82 | KCNH2 (0.48) | NR1H3NR1H2AR | |
| SCHEMBL25763803 | 0.75 | PIK3CD (0.37) | NR1H3HSD11B1PIK3CDNR1H2SCN9A | |
| SCHEMBL25763801 | 0.75 | PIK3CD (0.37) | NR1H3HSD11B1PIK3CDNR1H2SCN9A | |
| SCHEMBL24868587 | 0.74 | RXRA (0.34) | NR1H3HSD11B1NR1H2TRPA1AR | |
| SCHEMBL15481059 | 0.74 | PSMD14 (0.33) | NR1H3HSD11B1NR1H2TRPA1AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023116835-A1 | MULTI-PROTEIN DEGRADATION AGENT HAVING IMIDE SKELETON | 苏州开拓药业股份有限公司 | 2023-06-29 | — | — | WO | disclosed |