Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 9/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
| ▸ | KIT | P10721 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25763766 | 0.83 | CYP11B2 (0.52) | FYNGRIN1GRIN2BNR1H2NR1H3 | |
| SCHEMBL25764075 | 0.82 | AR (0.49) | GRIN1GRIN2BNR1H2NR1H3CYP11B2 | |
| SCHEMBL25764079 | 0.82 | ESR1 (0.39) | NR1H2NR1H3CYP11B2 | |
| SCHEMBL25764072 | 0.81 | MAP4K4 (0.40) | NR1H2NR1H3CYP11B2ALDH1A1GAA | |
| SCHEMBL25763768 | 0.80 | PGR (0.53) | FYNNTRK1SYKNR1H2NR1H3 | |
| SCHEMBL25763769 | 0.79 | KCNH2 (0.48) | GRIN1GRIN2BNR1H2NR1H3 | |
| SCHEMBL12303952 | 0.71 | ALDH1A1 (0.45) | CYP11B2SOS1ALDH1A1 | |
| SCHEMBL30602821 | 0.69 | ALDH1A1 (0.58) | FYNNTRK1ALDH1A1NOTUM | |
| SCHEMBL12299837 | 0.69 | L3MBTL1 (0.41) | ALDH1A1GAA | |
| SCHEMBL25764094 | 0.69 | ALDH1A1 (0.53) | GRIN1GRIN2BALDH1A1GAAATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023116835-A1 | MULTI-PROTEIN DEGRADATION AGENT HAVING IMIDE SKELETON | 苏州开拓药业股份有限公司 | 2023-06-29 | — | — | WO | disclosed |