Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | VEGFA | P15692 | 1/20 | 0.38 |
| ▸ | FLT1 | P17948 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25763766 | 0.86 | CYP11B2 (0.52) | NR1H3NR1H2GAAALDH1A1CYP11B2 | |
| SCHEMBL25764075 | 0.84 | AR (0.49) | NR1H3NR1H2GAAALDH1A1HPGD | |
| SCHEMBL25764079 | 0.84 | ESR1 (0.39) | PIK3CDSMN1; SMN2RAB9ANPC1NR1H3 | |
| SCHEMBL25763768 | 0.82 | PGR (0.53) | PGRSMN1; SMN2RAB9ANPC1NR1H3 | |
| SCHEMBL25771002 | 0.81 | MAP4K4 (0.43) | MAP4K4SMN1; SMN2RAB9ANPC1LMNA | |
| SCHEMBL25763764 | 0.81 | SMN1; SMN2 (0.47) | MAP4K4PGRPIK3CDSMN1; SMN2RAB9A | |
| SCHEMBL25763772 | 0.81 | FYN (0.43) | NR1H3NR1H2GAAALDH1A1CYP11B2 | |
| SCHEMBL25763769 | 0.81 | KCNH2 (0.48) | PGRNR1H3NR1H2DHODH | |
| SCHEMBL25763753 | 0.81 | MAP4K4 (0.44) | MAP4K4SMN1; SMN2RAB9ANPC1LMNA | |
| SCHEMBL25763756 | 0.80 | ESR2 (0.49) | MAP4K4SMN1; SMN2RAB9ANPC1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023116835-A1 | MULTI-PROTEIN DEGRADATION AGENT HAVING IMIDE SKELETON | 苏州开拓药业股份有限公司 | 2023-06-29 | — | — | WO | disclosed |