Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.40 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.40 |
| ▸ | HTR3B | O95264 | 2/20 | 0.40 |
| ▸ | HTR3A | P46098 | 2/20 | 0.40 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.40 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | CASP3 | P42574 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2582570 | 0.86 | SIGMAR1 (0.49) | SIGMAR1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL5145312 | 0.85 | NPC1 (0.41) | SIGMAR1CYP2A6TDP1CYP1A2MEN1 | |
| SCHEMBL348429 | 0.84 | SIGMAR1 (0.41) | SIGMAR1TDP1CYP1A2MEN1KMT2A | |
| SCHEMBL2256805 | 0.80 | SIGMAR1 (0.45) | SIGMAR1TDP1CYP1A2MEN1KMT2A | |
| SCHEMBL6542069 | 0.78 | SIGMAR1 (0.44) | SIGMAR1TDP1CYP1A2MEN1KMT2A | |
| SCHEMBL6541314 | 0.78 | SIGMAR1 (0.44) | SIGMAR1TDP1CYP1A2MEN1KMT2A | |
| SCHEMBL6542058 | 0.78 | SIGMAR1 (0.44) | SIGMAR1TDP1CYP1A2MEN1KMT2A | |
| SCHEMBL6542100 | 0.78 | SIGMAR1 (0.44) | SIGMAR1TDP1CYP1A2MEN1KMT2A | |
| SCHEMBL5143493 | 0.77 | ALDH1A1 (0.46) | SIGMAR1CYP2A6TDP1CYP1A2MEN1 | |
| SCHEMBL6422598 | 0.75 | CYP2A6 (0.54) | HTR3EHTR3BHTR3AHTR3DHTR3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8048541-B2 | Organic electroluminescence device | CITY UNIVERSITY OF HONG KONG (HK) | 2011-11-01 | — | — | US | disclosed |
| US-20100148662-A1 | ORGANIC ELECTROLUMINESCENCE DEVICE | CITY UNIVERSITY OF HONG KONG (HK) | 2010-06-17 | — | — | US | disclosed |
| US-7429662-B2 | Red-emitting electrophosphorescent devices | CITY UNIVERSITY OF HONG KONG (CN) | 2008-09-30 | — | — | US | disclosed |
| US-7232617-B2 | Electroluminescent devices | CITYU RESEARCH LIMITED (CN) | 2007-06-19 | — | — | US | disclosed |
| US-20060261730-A1 | Red-emitting electrophosphorescent devices | CITY UNIVERSITY OF HONG KONG (CN) | 2006-11-23 | — | — | US | disclosed |
| US-6861162-B2 | Doped thin films; multilayer; electrolytic cells; light emitting diodes | CITYU RESEARCH LTD. (CN) | 2005-03-01 | — | — | US | disclosed |
| US-6833202-B2 | Luminescent layer uses as salicylaldiminato Schiff bases or their metal complexes based on diaminomaleonitrile and salicylaldehyde derivatives as red-emitting materials; color chromaticity | CITY UNIVERSITY OF HONG KONG (CN) | 2004-12-21 | — | — | US | disclosed |
| US-20040180234-A1 | Electroluminescent devices | HONG KONG, CITY UNIVERSITY OF (CN) | 2004-09-16 | — | — | US | disclosed |
| US-20040151943-A1 | Electroluminescent devices | INTELLECTUAL VENTURES II LLC | 2004-08-05 | — | — | US | disclosed |
| US-20040043247-A1 | Organic electroluminescence devices using pyrazolo [3,4B] quinoxaline derivatives | INTELLECTUAL VENTURES HOLDING 57 LLC | 2004-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040180234-A1 | Electroluminescent devices | SLC25A13, AOC1, DDT | SIGMAR1 4190/4885HTR3E 3853/4885HTR3B 3531/4885 |
| US-20100148662-A1 | ORGANIC ELECTROLUMINESCENCE DEVICE | IK, CACNA2D3, CACNA2D4 | SIGMAR1 840/4885HTR3E 4352/4885HTR3B 4455/4885 |
| US-20040151943-A1 | Electroluminescent devices | SLCO2B1, SLCO2A1, HAX1 | SIGMAR1 22/4885HTR3E 568/4885HTR3B 848/4885 |
| US-20060261730-A1 | Red-emitting electrophosphorescent devices | IK, EED, SPR | SIGMAR1 1889/4885HTR3E 3830/4885HTR3B 3777/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.