Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25779359 | 0.94 | LMNA (0.31) | LMNA | |
| SCHEMBL28433372 | 0.82 | LMNA (0.43) | THRBLMNA | |
| SCHEMBL25779389 | 0.81 | CYP3A4 (0.36) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL25779336 | 0.81 | MEN1 (0.42) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL25779349 | 0.79 | LMNA (0.31) | LMNA | |
| SCHEMBL25779354 | 0.79 | MEN1 (0.39) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL3641605 | 0.76 | EPHX2 (0.32) | — | |
| SCHEMBL26743666 | 0.76 | LMNA (0.35) | THRBLMNA | |
| SCHEMBL13081849 | 0.76 | TDP1 (0.42) | THRBLMNA | |
| SCHEMBL6492390 | 0.75 | LMNA (0.41) | THRBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230212103-A1 | POLYETHYLENE GLYCOL DERIVATIVE AND USE THEREOF | HANMI PHARM. CO., LTD. (KR) | 2023-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230212103-A1 | POLYETHYLENE GLYCOL DERIVATIVE AND USE THEREOF | RPN2, MPDU1, RPN1 | MEN1 2947/4885THRB 3810/4885HTT 3083/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.