Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.38 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.38 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.38 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.38 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.38 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.38 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 2/20 | 0.38 |
| ▸ | HTR5A | P47898 | 2/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23875533 | 0.84 | SMN1; SMN2 (0.47) | MAPK1KDM4EALDH1A1HPGDHTT | |
| SCHEMBL25783763 | 0.83 | TBXAS1 (0.48) | MAPK1KDM4EALDH1A1LMNAHSD17B10 | |
| SCHEMBL25783627 | 0.75 | IDO1 (0.43) | MAPK1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL25783465 | 0.75 | IDO1 (0.43) | MAPK1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL25788656 | 0.71 | MEN1 (0.36) | MAPK1HTR2BHTR5ATDO2NQO2 | |
| SCHEMBL25784580 | 0.70 | KDM4E (0.41) | HTR2BHTR5ATDO2NQO2KDM4E | |
| SCHEMBL25783488 | 0.68 | KDM4E (0.38) | HTR2BHTR5ATDO2NQO2KDM4E | |
| Ammonia Solution, Strong SCHEMBL28650410 | 0.67 | HTR2B (0.58) | HTR2BHTR5ATDO2NQO2MEN1 | |
| SCHEMBL25783407 | 0.66 | NLRP3 (0.39) | HTR2BHTR5ATDO2KDM4EALDH1A1 | |
| SCHEMBL25783758 | 0.65 | SMN1; SMN2 (0.55) | MAPK1KDM4EALDH1A1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230174485-A1 | LIPOXYGENASE INHIBITORS | SRI INTERNATIONAL (US) | 2023-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230174485-A1 | LIPOXYGENASE INHIBITORS | ALOX15B, ALOX12, ALOX15 | MAPK1 1479/4885PRKAB2 2388/4885PRKAG1 2928/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.