Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 7/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.35 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10686251 | 0.84 | ALDH1A1 (0.58) | ALDH1A1TDP1TSHRCYP3A4HSD17B10 | |
| SCHEMBL25411924 | 0.84 | ALDH1A1 (0.37) | ALDH1A1TDP1TSHRCYP3A4MAPT | |
| SCHEMBL16739101 | 0.80 | VCP (0.40) | ALDH1A1TDP1TSHRCYP3A4MAPT | |
| SCHEMBL30186077 | 0.80 | ALDH1A1 (0.54) | ALDH1A1TDP1TSHRCYP3A4MEN1 | |
| SCHEMBL27857101 | 0.80 | ALDH1A1 (0.54) | ALDH1A1TDP1TSHRCYP3A4MEN1 | |
| SCHEMBL29686335 | 0.80 | VCP (0.40) | ALDH1A1TDP1TSHRCYP3A4MAPT | |
| SCHEMBL1199723 | 0.80 | ALDH1A1 (0.54) | ALDH1A1TDP1TSHRCYP3A4MEN1 | |
| SCHEMBL16738853 | 0.79 | TDP1 (0.49) | ALDH1A1TDP1MEN1MAPTKMT2A | |
| SCHEMBL30673293 | 0.79 | TDP1 (0.49) | ALDH1A1TDP1MEN1MAPTKMT2A | |
| SCHEMBL19783167 | 0.77 | ALDH1A1 (0.50) | ALDH1A1TDP1TSHRCYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230174485-A1 | LIPOXYGENASE INHIBITORS | SRI INTERNATIONAL (US) | 2023-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230174485-A1 | LIPOXYGENASE INHIBITORS | ALOX15B, ALOX12, ALOX15 | ALDH1A1 133/4885TDP1 1140/4885TSHR 4445/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.