Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 3/20 | 0.32 |
| ▸ | BLM | P54132 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TK2 | O00142 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | ALB | P02768 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8104285 | 0.83 | LMNA (0.41) | CYP1A2TSHRPMP22LMNA | |
| SCHEMBL2633815 | 0.70 | LMNA (0.41) | TK1BLMTSHRPMP22NPSR1 | |
| SCHEMBL28765909 | 0.69 | LMNA (0.42) | TK1BLMTSHRPMP22NPSR1 | |
| SCHEMBL2012504 | 0.69 | ALDH1A1 (0.43) | TK1BLMTSHRPMP22NPSR1 | |
| SCHEMBL13065052 | 0.69 | BLM (0.48) | TK1BLMCYP1A2CYP3A4TSHR | |
| SCHEMBL339966 | 0.68 | ALDH1A1 (0.41) | TK1BLMTSHRPMP22NPSR1 | |
| SCHEMBL3611848 | 0.68 | LMNA (0.41) | TK1BLMTSHRPMP22NPSR1 | |
| SCHEMBL1878105 | 0.68 | ALDH1A1 (0.43) | TK1BLMPMP22NPSR1ALDH1A1 | |
| SCHEMBL30841853 | 0.68 | ALDH1A1 (0.41) | TK1BLMTSHRPMP22NPSR1 | |
| SCHEMBL27583424 | 0.68 | ALDH1A1 (0.41) | TK1BLMTSHRPMP22NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2558577-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2013-02-20 | — | — | EP | disclosed |
| WO-2011127933-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2011-10-20 | — | — | WO | disclosed |