Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 3/20 | 0.49 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTR1B | P28222 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1986857 | 0.81 | HTR7 (0.49) | HTR7ROCK2CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL25319735 | 0.77 | HTR7 (0.54) | HTR7ROCK2CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL15545676 | 0.74 | HTR7 (0.51) | HTR7ROCK2CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL1988447 | 0.74 | ROCK2 (0.55) | HTR7ROCK2CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL19732163 | 0.73 | HTR7 (0.51) | HTR7ROCK2KDM4EPOLBL3MBTL1 | |
| SCHEMBL30061204 | 0.72 | HTR7 (0.49) | HTR7ROCK2CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL23875713 | 0.72 | HTR7 (0.49) | HTR7ROCK2CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL11448408 | 0.71 | HRH3 (0.56) | HTR7CYP1A2CYP2D6CYP2C19HRH3 | |
| SCHEMBL15786897 | 0.71 | ROCK2 (0.55) | HTR7ROCK2KDM4EMAPTHTR1B | |
| SCHEMBL7399293 | 0.71 | HTR7 (0.60) | HTR7ROCK2CYP1A2CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230174485-A1 | LIPOXYGENASE INHIBITORS | SRI INTERNATIONAL (US) | 2023-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230174485-A1 | LIPOXYGENASE INHIBITORS | ALOX15B, ALOX12, ALOX15 | HTR7 2208/4885ROCK2 1265/4885CYP1A2 66/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.