Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 1.00 |
| ▸ | HPGD | P15428 | 4/20 | 1.00 |
| ▸ | MEN1 | O00255 | 3/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 3/20 | 1.00 |
| ▸ | TSHR | P16473 | 2/20 | 1.00 |
| ▸ | LMNA | P02545 | 1/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 1/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 1/20 | 1.00 |
| ▸ | HTT | P42858 | 1/20 | 1.00 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA7 | P43166 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Haplamine SCHEMBL30203195 | 1.00 | ALDH1A1 (1.00) | ALDH1A1HSD17B10KDM4EHPGDMEN1 | |
| Flindersine SCHEMBL3125149 | 0.79 | HSD17B10 (1.00) | ALDH1A1HSD17B10KDM4EHPGDMEN1 | |
| Koenimbine SCHEMBL29581663 | 0.77 | MAPT (0.69) | ALDH1A1HSD17B10KDM4EHPGDMEN1 | |
| Claulansine F SCHEMBL29684000 | 0.76 | ALDH1A1 (0.61) | ALDH1A1HSD17B10KDM4EHPGDMEN1 | |
| SCHEMBL28829841 | 0.72 | KDM4E (0.55) | ALDH1A1HSD17B10KDM4EHPGDMEN1 | |
| SCHEMBL30929792 | 0.70 | MAPT (0.69) | ALDH1A1HSD17B10KDM4EHPGDMEN1 | |
| SCHEMBL12285521 | 0.66 | ABCG2 (0.83) | ALDH1A1HSD17B10KDM4EHPGDMEN1 | |
| SCHEMBL3124589 | 0.66 | ALDH1A1 (0.63) | ALDH1A1HSD17B10KDM4EHPGDMEN1 | |
| SCHEMBL2597652 | 0.66 | ALDH1A1 (1.00) | ALDH1A1HSD17B10KDM4EHPGDMEN1 | |
| SCHEMBL29391519 | 0.66 | ALDH1A1 (1.00) | ALDH1A1HSD17B10KDM4EHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024078534-A1 | INTERFERING RNA FOR INHIBITING EXPRESSION OF MELANOPHILIN (MLPH) GENE, AND APPLICATION THEREOF | 北京键凯科技股份有限公司 | 2024-04-18 | — | — | WO | disclosed |
| CN-117866955-A | Interference RNA for inhibiting expression of melanin avidin (MLPH) gene and application thereof | 北京键凯科技股份有限公司 | 2024-04-12 | — | — | CN | disclosed |
| CN-104428036-A | Polypeptides and their use | NOVABIOTICS LTD | 2015-03-18 | — | — | CN | disclosed |
| EP-2825261-A1 | POLYPEPTIDES AND THEIR USE | Novabiotics Limited (GB) | 2015-01-21 | — | — | EP | disclosed |
| US-20140155321-A1 | Polypeptides and Their Use | NOVABIOTICS LIMITED (GB) | 2014-06-05 | — | — | US | disclosed |
| WO-2013136040-A1 | POLYPEPTIDES AND THEIR USE | NOVABIOTICS LIMITED (GB) | 2013-09-19 | — | — | WO | disclosed |
| EP-1910844-B1 | CROSS-BETA STRUCTURE BINDING COMPOUNDS | CROSSBETA BIOSCIENCES BV (NL) | 2012-04-18 | — | — | EP | disclosed |
| EP-2386861-A2 | Cross-ß structure binding compounds | Crossbeta Biosciences B.V. (NL) | 2011-11-16 | — | — | EP | disclosed |
| US-20080267948-A1 | Croos-B Structure Binding Compounds | CROSSBETA BIOSCIENCES B.V. (NL) | 2008-10-30 | — | — | US | disclosed |
| US-20080267948-A1 | Croos-B Structure Binding Compounds | CROSSBETA BIOSCIENCES B.V. (NL) | 2008-10-30 | — | — | US | disclosed |
| WO-2007008072-A2 | CROSS-ß STRUCTURE BINDING COMPOUNDS | CROSSBETA BIOSCIENCES B.V. (NL) | 2007-01-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080267948-A1 | Croos-B Structure Binding Compounds | CACYBP, TBCB, MYCBP | ALDH1A1 3494/4885HSD17B10 982/4885KDM4E 4553/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.