Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | HPGD | P15428 | 2/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | XBP1 | P17861 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | PARP1 | P09874 | 2/20 | 0.42 |
| ▸ | TNKS | O95271 | 1/20 | 0.42 |
| ▸ | GPR3 | P46089 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5902327 | 0.80 | HSD17B10 (0.67) | HSD17B10KDM4EALDH1A1MEN1LMNA | |
| Haplamine SCHEMBL257952 | 0.79 | ALDH1A1 (1.00) | HSD17B10KDM4EALDH1A1MEN1LMNA | |
| Haplamine SCHEMBL30203195 | 0.79 | ALDH1A1 (1.00) | HSD17B10KDM4EALDH1A1MEN1LMNA | |
| SCHEMBL29035311 | 0.76 | KMT2A (0.66) | HSD17B10KDM4EALDH1A1MEN1LMNA | |
| SCHEMBL30366382 | 0.76 | KMT2A (0.66) | HSD17B10KDM4EALDH1A1MEN1LMNA | |
| Grinimibine SCHEMBL4132680 | 0.72 | MAPT (1.00) | HSD17B10KDM4EALDH1A1MEN1LMNA | |
| SCHEMBL6272145 | 0.72 | HSD17B10 (0.56) | HSD17B10KDM4EALDH1A1MEN1LMNA | |
| SCHEMBL28935130 | 0.67 | KDM4E (0.57) | HSD17B10KDM4EALDH1A1MEN1LMNA | |
| SCHEMBL9626803 | 0.65 | HSD17B10 (0.48) | HSD17B10KDM4EALDH1A1MEN1LMNA | |
| Flindersine SCHEMBL31655421 | 0.65 | HSD17B10 (0.48) | HSD17B10KDM4EALDH1A1MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103435584-A | Preparation method of collinin | NANJING TONGZE AGRICULTURE SCIENCE & TECHNOLOGY CO LTD | 2013-12-11 | — | — | CN | claimed |
| US-10195216-B1 | Antimicrobial activity and oil compositions of Costus speciosus (KOEN) | KING ABDULAZIZ UNIVERSITY (SA) | 2019-02-05 | — | — | US | disclosed |
| CN-104428036-A | Polypeptides and their use | NOVABIOTICS LTD | 2015-03-18 | — | — | CN | disclosed |
| CN-103435584-A | Preparation method of collinin | NANJING TONGZE AGRICULTURE SCIENCE & TECHNOLOGY CO LTD | 2013-12-11 | — | — | CN | disclosed |
| US-20100009927-A1 | Anti-Inflammatory and Anti-Allergy Extracts from Nettle | HERBALSCIENCE GROUP LLC (US) | 2010-01-14 | — | — | US | disclosed |
| EP-0872903-B1 | Method for making hydrogen storage alloy powder and electrode comprising the alloy powder | SHINETSU CHEMICAL CO (JP) | 2001-10-04 | — | — | EP | disclosed |
| US-6277519-B1 | QUENCHING AN ALLOY MELT; COMMINUTION | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2001-08-21 | — | — | US | disclosed |
| EP-0843371-B1 | Hydrogen storage alloy powder and an electrode comprising the same | SHINETSU CHEMICAL CO (JP) | 2000-10-18 | — | — | EP | disclosed |
| US-6096144-A | TREATING WITH ACIDIC OR ALKALINE SOLUTION OF CONJUGATED UNSATURATED COMPOUND WITH AT LEAST 5 BONDS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2000-08-01 | — | — | US | disclosed |
| US-5968225-A | POWDER HAVING METALLIC NICKEL PRESENT ON OR IN SURFACE IN AN AMOUNT TO IMPART FAVORABLE MAGNETIZATION INTENSITY; BATTERIES | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1999-10-19 | — | — | US | disclosed |
| US-5858571-A | TREATING A PULVERIZED HYDROGEN ABSORBING ALLOY WITH A SOLUTION COMPRISING A CONJUGATED UNSATURATED COMPOUND | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1999-01-12 | — | — | US | disclosed |
| EP-0872903-A1 | Method for making hydrogen storage alloy powder and electrode comprising the alloy powder | Shin-Etsu Chemical Co., Ltd. (JP) | 1998-10-21 | — | — | EP | disclosed |
| EP-0843371-A1 | Hydrogen storage alloy powder and an electrode comprising the same | Shin-Etsu Chemical Co., Ltd. (JP) | 1998-05-20 | — | — | EP | disclosed |
| US-5070088-A | Pyranyl quinoline calcium channel blockers | E. R. SQUIBB & SONS, INC. (US) | 1991-12-03 | — | — | US | disclosed |
| EP-0172427-B1 | PROCESS FOR PRODUCTION OF VINYL CHLORIDE POLYMER | Shin-Etsu Chemical Co., Ltd. (JP) | 1989-07-05 | — | — | EP | disclosed |
| US-4758639-A | Process for production of vinyl polymer | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1988-07-19 | — | — | US | disclosed |
| US-4757124-A | Suspension or emulsion polymerizing vinyl chloride monomer or mixture of vinyl chloride with vinyl monomer copolymerizable therewith in reactor with walls coated with antiscaling compound containing dye or pigments | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0172427-A2 | Process for production of vinyl chloride polymer | Shin-Etsu Chemical Co., Ltd. (JP) | 1986-02-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10195216-B1 | Antimicrobial activity and oil compositions of Costus speciosus (KOEN) | CUTA, PTGES, FASN | HSD17B10 594/4885KDM4E 1811/4885ALDH1A1 859/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.