Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 3/20 | 0.37 |
| ▸ | CNR2 | P34972 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.33 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.33 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1921739 | 0.86 | L3MBTL1 (0.43) | LMNAHPGDKDM4ESIGMAR1L3MBTL1 | |
| SCHEMBL1115239 | 0.83 | HPGD (0.47) | LMNAHPGD | |
| SCHEMBL969710 | 0.83 | HPGD (0.52) | LMNAHPGD | |
| SCHEMBL2186819 | 0.82 | POLB (0.51) | HPGDL3MBTL1POLB | |
| SCHEMBL1642860 | 0.81 | HPGD (0.55) | LMNAHPGDL3MBTL1 | |
| SCHEMBL1566654 | 0.79 | SIGMAR1 (0.57) | HPGDSIGMAR1POLB | |
| SCHEMBL4538878 | 0.79 | KMT2A (0.41) | HPGDKDM4ESIGMAR1L3MBTL1POLB | |
| SCHEMBL6347565 | 0.79 | HPGD (0.46) | FAAHHPGDKDM4E | |
| SCHEMBL971067 | 0.79 | HPGD (0.51) | HPGDPOLB | |
| SCHEMBL4352484 | 0.76 | ACHE (0.59) | LMNAHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066647-B1 | BENZOXAZOLES AND OXAZOLOPYRIDINES BEING USEFUL AS JANUS KINASES INHIBITORS | NOVARTIS AG (CH) | 2011-11-09 | — | — | EP | claimed |