SCHEMBL2579808

SCHEMBL2579808

CC(C)=C[SiH2]c1ccc(-c2ccc([SiH2]C=C(C)C)cc2)cc1

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL758547 0.92
SCHEMBL11360965 0.81 NPC1 (0.37) HTTSMN1; SMN2L3MBTL1
SCHEMBL3378641 0.81 NOS1 (0.39) SMN1; SMN2L3MBTL1
SCHEMBL10559149 0.78
SCHEMBL10546504 0.78
SCHEMBL11352866 0.78 NOS3 (0.42)
SCHEMBL11355626 0.76 NOS1 (0.46) SMN1; SMN2
SCHEMBL6114211 0.73
Potassium Ion SCHEMBL11351404 0.73 CA2 (0.41)
SCHEMBL28753437 0.72 ENPP2 (0.35) HTTSMN1; SMN2L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8048977-B2 Organosilicon polymers E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-11-01 US claimed
US-20090069525-A1 ORGANOSILICON POLYMERS E. I. DU PONT DE NEMOURS AND COMPANY 2009-03-12 US claimed
WO-2007130014-A1 ORGANOSILICON POLYMERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-11-15 WO claimed
US-8048977-B2 Organosilicon polymers E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-11-01 US disclosed
US-20090069525-A1 ORGANOSILICON POLYMERS E. I. DU PONT DE NEMOURS AND COMPANY 2009-03-12 US disclosed
WO-2007130014-A1 ORGANOSILICON POLYMERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-11-15 WO disclosed