Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 1/20 | 0.51 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | CCR1 | P32246 | 2/20 | 0.50 |
| ▸ | CCR5 | P51681 | 2/20 | 0.50 |
| ▸ | CCR8 | P51685 | 2/20 | 0.50 |
| ▸ | METAP1 | P53582 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.50 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31070227 | 1.00 | GRIA1 (0.51) | GRIA1GRIA3PDE4DKDM4ELMNA | |
| SCHEMBL30102603 | 1.00 | GRIA1 (0.51) | GRIA1GRIA3PDE4DKDM4ELMNA | |
| SCHEMBL5826054 | 0.98 | GRIA1 (0.50) | GRIA1GRIA3PDE4DKDM4ELMNA | |
| SCHEMBL18411239 | 0.85 | GRIA1 (0.44) | GRIA1GRIA3PDE4DKDM4ELMNA | |
| Dipyridyl SCHEMBL27792926 | 0.85 | KDM4E (0.64) | GRIA1GRIA3PDE4DKDM4ELMNA | |
| SCHEMBL28856972 | 0.84 | GRIA1 (0.43) | GRIA1GRIA3PDE4DKDM4ELMNA | |
| SCHEMBL30814370 | 0.84 | GRIA1 (0.43) | GRIA1GRIA3PDE4DKDM4ELMNA | |
| SCHEMBL2363578 | 0.84 | NISCH (0.50) | GRIA1GRIA3PDE4DKDM4ELMNA | |
| 2-Picolinic Acid SCHEMBL5670754 | 0.83 | LMNA (0.56) | GRIA1GRIA3PDE4DKDM4ELMNA | |
| SCHEMBL18411456 | 0.82 | KDM4E (0.52) | GRIA1GRIA3PDE4DKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5454975-A | Electrooptical display | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1995-10-03 | — | — | US | claimed |
| CN-117756794-A | Nitrogen-containing heterocyclic compound, and preparation method and application thereof | 和径医药科技（上海）有限公司 | 2024-03-26 | — | — | CN | disclosed |
| US-20230365606-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2023-11-16 | — | — | US | disclosed |
| US-20230371358-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2023-11-16 | — | — | US | disclosed |
| US-20230357296-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2023-11-09 | — | — | US | disclosed |
| US-20230348510-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2023-11-02 | — | — | US | disclosed |
| US-20230348509-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2023-11-02 | — | — | US | disclosed |
| US-20230345811-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2023-10-26 | — | — | US | disclosed |
| US-20230345812-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2023-10-26 | — | — | US | disclosed |
| US-20230345811-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2023-10-26 | — | — | US | disclosed |
| WO-2002076983-A1 | IMIDAZO-PYRIMIDINE DERIVATIVES AS LIGANDS FOR GABA RECEPTORS | MERCK SHARP & DOHME LIMITED (GB) | 2002-10-03 | — | — | WO | disclosed |
| US-6400433-B1 | Circularly polarizing plate comprising linearly polarizing membrane and quarter wave plate | FUJI PHOTO FILM CO., LTD. (JP) | 2002-06-04 | — | — | US | disclosed |
| EP-0700983-B1 | Electrooptical liquid crystal system | MERCK PATENT GMBH (DE) | 2001-07-11 | — | — | EP | disclosed |
| EP-1079244-A2 | Orientation layer containing (meth)acrylic copolymer having hydrophobic repeating units | FUJI PHOTO FILM CO., LTD. (JP) | 2001-02-28 | — | — | EP | disclosed |
| US-5958290-A | ELECTROOPTICAL APPARATUS WITH DIELECTRIC LIQUID CRYSTALS FOR RADIATION TRANSPARENT MEDIUM | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1999-09-28 | — | — | US | disclosed |
| EP-0511487-B1 | Electro-optical liquid crystal system | MERCK PATENT GMBH (DE) | 1996-05-29 | — | — | EP | disclosed |
| EP-0700983-A2 | Electrooptical liquid crystal system | MERCK PATENT GmbH (DE) | 1996-03-13 | — | — | EP | disclosed |
| US-5454975-A | Electrooptical display | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1995-10-03 | — | — | US | disclosed |
| US-5344587-A | Nitriles | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1994-09-06 | — | — | US | disclosed |
| EP-0511487-A1 | Electro-optical liquid crystal system | MERCK PATENT GmbH (DE) | 1992-11-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230345812-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | OCIAD1, OPRD1, OCIAD2 | GRIA1 327/4885GRIA3 760/4885PDE4D 4433/4885 |
| US-20230357296-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | OPRD1, OXER1, LBR | GRIA1 274/4885GRIA3 1069/4885PDE4D 4383/4885 |
| US-20230348510-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | LBR, OXER1, OXSR1 | GRIA1 136/4885GRIA3 420/4885PDE4D 4737/4885 |
| US-20230348509-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | MLX, OCIAD1, LBR | GRIA1 977/4885GRIA3 1223/4885PDE4D 4534/4885 |
| US-20230371358-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | LIFR, SOD1, ROS1 | GRIA1 48/4885GRIA3 17/4885PDE4D 4837/4885 |
| US-20230365606-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | OXER1, OPRD1, OXSR1 | GRIA1 281/4885GRIA3 273/4885PDE4D 3975/4885 |
| US-20230345811-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | OPRD1, L1CAM, OPRM1 | GRIA1 2754/4885GRIA3 1983/4885PDE4D 4250/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.