Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.46 |
| ▸ | HTR1A | P08908 | 2/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | TLR8 | Q9NR97 | 6/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 2/20 | 0.40 |
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | FBP1 | P09467 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23422372 | 0.86 | ELANE (0.44) | DRD2HTR1AHTR2ATLR8TLR7 | |
| SCHEMBL2335323 | 0.83 | DRD2 (0.46) | DRD2HTR1AHTR2ADRD3ASH1L | |
| SCHEMBL394985 | 0.79 | DRD2 (0.42) | DRD2HTR1AHTR2ADRD3ASH1L | |
| SCHEMBL9722755 | 0.73 | ALDH1A1 (0.57) | DRD2HTR1AHTR2ATLR8TLR7 | |
| SCHEMBL30967498 | 0.73 | TLR8 (0.49) | TLR8SMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL30488147 | 0.73 | HSD17B10 (0.43) | DRD2HTR1AHTR2AASH1LSMN1; SMN2 | |
| SCHEMBL25273864 | 0.73 | HSD17B10 (0.43) | DRD2HTR1AHTR2AASH1LSMN1; SMN2 | |
| SCHEMBL289210 | 0.73 | SMN1; SMN2 (0.56) | TLR8TLR7ASH1LSMN1; SMN2ALDH1A1 | |
| SCHEMBL30003135 | 0.73 | SMN1; SMN2 (0.56) | TLR8TLR7ASH1LSMN1; SMN2ALDH1A1 | |
| SCHEMBL5260809 | 0.72 | ASH1L (0.46) | ASH1LSMN1; SMN2ALDH1A1GAANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023133181-A1 | KRAS INHIBITORS | THERAS, INC. (US) | 2023-07-13 | — | — | WO | disclosed |