Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | ACACA | Q13085 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25273864 | 1.00 | HSD17B10 (0.43) | HSD17B10HTTKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL23422372 | 0.79 | ELANE (0.44) | HSD17B10ALDH1A1SMN1; SMN2MAPTNPC1 | |
| SCHEMBL984327 | 0.75 | ILK (0.59) | HSD17B10KDM4EALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL25278238 | 0.74 | MAPK9 (0.47) | HSD17B10KDM4EALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL25801523 | 0.73 | DRD2 (0.46) | HTTALDH1A1SMN1; SMN2MAPTNPC1 | |
| SCHEMBL28842276 | 0.72 | ALDH1A1 (0.46) | HSD17B10KDM4EALDH1A1HPGDGAA | |
| SCHEMBL394985 | 0.72 | DRD2 (0.42) | ALDH1A1SMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL27429903 | 0.72 | ALDH1A1 (0.47) | HSD17B10KDM4EALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL12377717 | 0.71 | ALDH1A1 (0.49) | HSD17B10KDM4EALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL84829 | 0.71 | CYP3A4 (0.57) | KDM4EALDH1A1MAPTHPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107630-A2 | AMINO ALCOHOL COMPOUNDS AND USES THEREOF | Kineta, Inc. (US) | 2023-06-15 | — | — | WO | disclosed |