Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.34 |
| ▸ | FBP1 | P09467 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26580905 | 0.79 | GPR55 (0.32) | ELANE | |
| SCHEMBL24351779 | 0.78 | RPS6KA2 (0.33) | — | |
| SCHEMBL27052027 | 0.67 | ALDH1A1 (0.33) | — | |
| SCHEMBL14327833 | 0.66 | MTNR1A (0.31) | — | |
| SCHEMBL26580906 | 0.66 | GPR55 (0.32) | ELANEFBP1HDAC6 | |
| SCHEMBL24351118 | 0.65 | FBP1 (0.33) | FBP1HDAC6 | |
| SCHEMBL12032783 | 0.64 | GPR55 (0.35) | ELANEFBP1 | |
| SCHEMBL19808453 | 0.64 | ELANE (0.44) | ELANEFBP1 | |
| SCHEMBL25113501 | 0.62 | FBP1 (0.36) | FBP1HDAC6 | |
| SCHEMBL24251928 | 0.60 | GABRP (0.36) | ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023225252-A1 | COMPOSITIONS AND METHODS FOR INHIBITION OF RAS | THERAS, INC. (US) | 2023-11-23 | — | — | WO | disclosed |
| WO-2023133183-A1 | KRAS INHIBITORS | THERAS, INC. (US) | 2023-07-13 | — | — | WO | disclosed |
| WO-2023133181-A1 | KRAS INHIBITORS | THERAS, INC. (US) | 2023-07-13 | — | — | WO | disclosed |