SCHEMBL25802466

SCHEMBL25802466

Cc1cc(C)cc(N2c3ccccc3N(Cc3ccc(N4c5ccccc5N(C)c5ccccc54)cc3)c3ccccc32)c1

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TP53 P04637 4/20 0.41
LMNA P02545 1/20 0.41
POLB P06746 1/20 0.39
TSHR P16473 2/20 0.36
MAPT P10636 5/20 0.35
GRM5 P41594 1/20 0.34
HTT P42858 1/20 0.33
ADRA1D P25100 1/20 0.33
ADRA1A P35348 1/20 0.33
ADRA1B P35368 1/20 0.33
RXFP1 Q9HBX9 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25802442 0.83 MAOA (0.43) LMNAPOLBMAPT
SCHEMBL25802464 0.82 TP53 (0.45) TP53LMNAPOLBTSHRMAPT
SCHEMBL9481198 0.80 LMNA (0.60) TP53LMNAPOLBTSHRMAPT
SCHEMBL4571040 0.74 RXFP1 (0.53) TP53LMNAPOLBTSHRRXFP1
SCHEMBL20788946 0.74 ELANE (0.46) LMNATSHRMAPT
SCHEMBL29206307 0.73 MGLL (0.48) TP53LMNAPOLBMAPTADRA1A
SCHEMBL20788948 0.70 HSP90AA1 (0.52) LMNAMAPT
SCHEMBL19466035 0.70 MAPT (0.38) LMNAMAPTADRA1ARXFP1
SCHEMBL18905737 0.69 MAPT (0.45) LMNAPOLBMAPTGRM5HTT
SCHEMBL12251824 0.68 MAOA (0.44) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11692065-B2 Phenazine copolymers and uses thereof CORNELL UNIVERSITY (US) 2023-07-04 US disclosed