Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 9/20 | 0.55 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.48 |
| ▸ | PDE8B | O95263 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25794260 | 0.82 | USP28 (0.74) | KDM1AUSP28PDE8BMEN1KMT2A | |
| SCHEMBL25809849 | 0.82 | USP28 (0.69) | KDM1AUSP28PDE8BMEN1KMT2A | |
| SCHEMBL25808562 | 0.74 | USP28 (0.53) | KDM1AUSP28MEN1KMT2ALMNA | |
| SCHEMBL25809918 | 0.72 | KDM1A (0.66) | KDM1AUSP28MEN1KMT2A | |
| SCHEMBL25794195 | 0.68 | USP28 (0.81) | KDM1AUSP28PDE8BMEN1KMT2A | |
| SCHEMBL25794261 | 0.68 | KDM1A (0.57) | KDM1AUSP28MEN1KMT2ALMNA | |
| SCHEMBL25794224 | 0.66 | USP28 (1.00) | KDM1AUSP28MEN1KMT2ALMNA | |
| SCHEMBL4918962 | 0.65 | ALDH1A1 (0.66) | MEN1KMT2ALMNAKDM4EALDH1A1 | |
| SCHEMBL9666546 | 0.64 | PDE8B (0.65) | USP28PDE8BMEN1KMT2ALMNA | |
| SCHEMBL25794305 | 0.64 | USP28 (0.78) | USP28PDE8BMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122298-A1 | PROTEIN STABILIZING COMPOUNDS CONTAINING USP28 AND/OR USP25 TARGETING LIGANDS | Stablix, Inc. (US) | 2023-06-29 | — | — | WO | disclosed |