Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 12/20 | 0.66 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25809849 | 0.90 | USP28 (0.69) | KDM1AUSP28KMT2AMEN1 | |
| SCHEMBL25795472 | 0.80 | USP28 (0.83) | KDM1AUSP28KMT2AMEN1 | |
| SCHEMBL25795474 | 0.80 | USP28 (0.68) | KDM1AUSP28KMT2AMEN1 | |
| SCHEMBL25795475 | 0.80 | KDM1A (0.56) | KDM1AUSP28 | |
| SCHEMBL4918962 | 0.79 | ALDH1A1 (0.66) | KMT2AMEN1 | |
| SCHEMBL25794195 | 0.76 | USP28 (0.81) | KDM1AUSP28KMT2AMEN1 | |
| SCHEMBL3393873 | 0.75 | ADORA2A (0.62) | KMT2AMEN1 | |
| SCHEMBL14911849 | 0.74 | CNR2 (0.65) | KMT2AMEN1 | |
| SCHEMBL5264056 | 0.74 | ADORA3 (0.73) | — | |
| SCHEMBL25794224 | 0.73 | USP28 (1.00) | KDM1AUSP28KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122298-A1 | PROTEIN STABILIZING COMPOUNDS CONTAINING USP28 AND/OR USP25 TARGETING LIGANDS | Stablix, Inc. (US) | 2023-06-29 | — | — | WO | disclosed |