Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3A | Q14432 | 3/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.41 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.41 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.41 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.38 |
| ▸ | ALB | P02768 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.38 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.38 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8660992 | 0.93 | PDE3A (0.42) | PDE3APDE4DSLC29A1LMNATHRB | |
| SCHEMBL7775023 | 0.92 | PDE3A (0.44) | PDE3APDE4DSLC29A1LMNATHRB | |
| SCHEMBL5155774 | 0.90 | PDE3A (0.41) | PDE3APDE4DSLC29A1LMNATHRB | |
| SCHEMBL4971926 | 0.86 | PDE3A (0.46) | PDE3APDE4DSLC29A1LMNATHRB | |
| SCHEMBL7776347 | 0.84 | PDE3A (0.36) | PDE3APDE4DSLC29A1LMNATHRB | |
| SCHEMBL1962181 | 0.84 | PDE3A (0.45) | PDE3APDE4DSLC29A1LMNATHRB | |
| SCHEMBL28805006 | 0.82 | PDE3A (0.43) | PDE3APDE4DSLC29A1LMNATHRB | |
| SCHEMBL6408356 | 0.81 | PDE3A (0.43) | PDE3APDE4DSLC29A1LMNATHRB | |
| SCHEMBL16245248 | 0.81 | PDE3A (0.45) | PDE3APDE4DSLC29A1LMNATHRB | |
| SCHEMBL31342963 | 0.81 | PDE3A (0.45) | PDE3APDE4DSLC29A1LMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8048659-B1 | Conjugated polymer tag complexes | LEIF ROBERT C | 2011-11-01 | — | — | US | disclosed |
| US-6825331-B2 | DIAGNOSTIC HYBRIDIZATION PROBES; BIOCHEMICAL CONJUGATION | ISIS PHARMACEUTICALS, INC. | 2004-11-30 | — | — | US | disclosed |
| US-20030113769-A1 | Aminooxy functionalized oligomers, oligomer arrays and methods of using them | IONIS PHARMACEUTICALS, INC. | 2003-06-19 | — | — | US | disclosed |
| US-6576752-B1 | Oligonucleotide comprising a plurality of nucleotide units of given structure; useful for diagnostic, therapeutic and investigative purposes | ISIS PHARMACEUTICALS, INC. | 2003-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030113769-A1 | Aminooxy functionalized oligomers, oligomer arrays and methods of using them | RNGTT, RNMT, DCLRE1B | PDE3A 4335/4885PDE4D 3960/4885SLC29A1 759/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.