Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9532397 | 0.83 | NPSR1 (0.37) | MAOBDRD3KDM4EADRA2AADRA2B | |
| SCHEMBL9531785 | 0.83 | SIGMAR1 (0.35) | KDM1AMAOAMAOB | |
| SCHEMBL9531388 | 0.81 | ALOX12 (0.36) | ALOX12KDM1AMAOAMAOBDRD3 | |
| SCHEMBL9530955 | 0.72 | KMT2A (0.38) | ALOX12KDM4EADRA2AADRA2BADRA2C | |
| SCHEMBL9532323 | 0.71 | MAOB (0.36) | KDM1AMAOBKDM4EL3MBTL1NPSR1 | |
| SCHEMBL9531466 | 0.71 | SIGMAR1 (0.34) | ALOX12KDM1AMAOAMAOBKDM4E | |
| SCHEMBL9532845 | 0.71 | CHRM2 (0.31) | KDM1AMAOAMAOB | |
| SCHEMBL2581169 | 0.70 | MAOB (0.33) | MAOBKMT2AALDH1A1 | |
| SCHEMBL7159531 | 0.69 | ALDH1A1 (0.37) | ALOX12ALDH1A1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL29174116 | 0.68 | MAOB (0.32) | MAOBKDM4EKMT2AALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0314852-B1 | Process for the preparation of 1-substituted imidazole-carbonic acid and derivatives | CIBA GEIGY AG (CH) | 1993-11-18 | — | — | EP | disclosed |
| US-4921955-A | Process for the synthesis of 1-substituted imidazole-5-carboxylic acids and carboxylic acid derivatives | CIBA-GEIGY CORPORATION (US) | 1990-05-01 | — | — | US | disclosed |
| EP-0314852-A2 | Process for the preparation of 1-substituted imidazole-carbonic acid and derivatives | CIBA-GEIGY AG (CH) | 1989-05-10 | — | — | EP | disclosed |