Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 8/20 | 0.67 |
| ▸ | PLG | P00747 | 1/20 | 0.61 |
| ▸ | PLAU | P00749 | 1/20 | 0.61 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.55 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.53 |
| ▸ | FLT3 | P36888 | 1/20 | 0.53 |
| ▸ | F7 | P08709 | 1/20 | 0.49 |
| ▸ | F3 | P13726 | 1/20 | 0.49 |
| ▸ | DAO | P14920 | 1/20 | 0.49 |
| ▸ | GPR183 | P32249 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24019647 | 0.87 | F7 (0.66) | ALOX15HRH4FLT3F7F3 | |
| SCHEMBL16795745 | 0.85 | ALOX15 (0.61) | ALOX15PLGPLAUHRH4PDGFRB | |
| SCHEMBL23835754 | 0.81 | ALOX15 (0.69) | ALOX15HRH4PDGFRBFLT3F7 | |
| SCHEMBL18257927 | 0.81 | PLG (0.61) | ALOX15PLGPLAUDAOIDO1 | |
| SCHEMBL615882 | 0.80 | ALOX15 (1.00) | ALOX15PDGFRBFLT3 | |
| SCHEMBL30190576 | 0.80 | ALOX15 (1.00) | ALOX15PDGFRBFLT3 | |
| SCHEMBL671001 | 0.80 | F7 (0.74) | ALOX15HRH4PDGFRBFLT3F7 | |
| SCHEMBL30310328 | 0.80 | F7 (0.74) | ALOX15HRH4PDGFRBFLT3F7 | |
| SCHEMBL24019644 | 0.78 | FLT3 (0.63) | PLGPLAUHRH4PDGFRBFLT3 | |
| SCHEMBL30148093 | 0.78 | IDO1 (0.66) | PLGPLAUHRH4PDGFRBFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230212152-A1 | INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF | Pardes Biosciences, Inc. | 2023-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230212152-A1 | INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF | CTRL, CTSL, CTSV | ALOX15 1455/4885PLG 173/4885PLAU 494/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.