Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CTPS1 | P17812 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.33 |
| ▸ | TOP2A | P11388 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25812590 | 0.91 | LMNA (0.38) | LMNAPOLBSMN1; SMN2MAPTTP53 | |
| SCHEMBL25813023 | 0.90 | LMNA (0.38) | LMNAPOLBSMN1; SMN2MAPTTP53 | |
| SCHEMBL25812585 | 0.90 | ALDH1A1 (0.39) | LMNAPOLBSMN1; SMN2MAPTHTT | |
| SCHEMBL25294461 | 0.81 | GPR119 (0.39) | MAPTTP53HTTCTPS1KDM4E | |
| SCHEMBL25812992 | 0.80 | KMT2A (0.33) | LMNAPOLBSMN1; SMN2MAPTTP53 | |
| SCHEMBL25291390 | 0.79 | LMNA (0.35) | LMNAPOLBSMN1; SMN2MAPTTP53 | |
| SCHEMBL25812567 | 0.78 | ALDH1A1 (0.40) | LMNAPOLBSMN1; SMN2MAPTTP53 | |
| SCHEMBL25298309 | 0.78 | NR1D1 (0.40) | MAPTTP53HTTCTPS1KDM4E | |
| SCHEMBL30803074 | 0.77 | PARP15 (0.46) | LMNAPOLBSMN1; SMN2MAPTTP53 | |
| SCHEMBL28308732 | 0.77 | PARP15 (0.46) | LMNAPOLBSMN1; SMN2MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219931-A1 | FUSED HETEROARYL HYDROXAMATES AS STING AGONISTS | BISICHEM CO., LTD. (KR) | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219931-A1 | FUSED HETEROARYL HYDROXAMATES AS STING AGONISTS | STING1, IRF3, IFNAR1 | LMNA 2977/4885POLB 183/4885SMN1; SMN2 3686/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.