Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EYA3 | Q99504 | 4/20 | 0.44 |
| ▸ | SLC22A12 | Q96S37 | 8/20 | 0.42 |
| ▸ | TTR | P02766 | 4/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.38 |
| ▸ | EYA2 | O00167 | 1/20 | 0.38 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.38 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALB | P02768 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25814856 | 0.91 | SLC22A12 (0.48) | EYA3SLC22A12TTRCYP2C19CYP2C9 | |
| SCHEMBL25814853 | 0.83 | SLC22A12 (0.58) | EYA3SLC22A12TTRCYP2C19CYP2C9 | |
| SCHEMBL25814823 | 0.83 | SLC22A12 (0.62) | EYA3SLC22A12TTRCYP2C19CYP2C9 | |
| SCHEMBL25814848 | 0.82 | EYA3 (0.62) | EYA3SLC22A12TTRCYP2C19CYP2C9 | |
| SCHEMBL25814844 | 0.80 | SLC22A12 (0.49) | EYA3SLC22A12TTRCYP2C19CYP2C9 | |
| SCHEMBL25814819 | 0.72 | SLC22A12 (0.73) | EYA3SLC22A12TTRCYP2C19CYP2C9 | |
| SCHEMBL25814838 | 0.70 | SLC22A12 (0.56) | EYA3SLC22A12TTRCYP2C19CYP2C9 | |
| SCHEMBL25814802 | 0.69 | EYA3 (0.81) | EYA3SLC22A12TTRCYP2C19CYP2C9 | |
| SCHEMBL25814817 | 0.65 | SLC22A12 (0.84) | EYA3SLC22A12TTRCYP2C19CYP2C9 | |
| SCHEMBL25814835 | 0.64 | SLC22A12 (0.65) | EYA3SLC22A12TTRCYP2C19CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230218563-A1 | METHODS FOR TREATING OR PREVENTING CHRONIC KIDNEY DISEASE | ARTHROSI THERAPEUTICS, INC. | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230218563-A1 | METHODS FOR TREATING OR PREVENTING CHRONIC KIDNEY DISEASE | ATP6V1B1, REN, CYP27B1 | EYA3 3141/4885SLC22A12 620/4885TTR 201/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.