Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K1 | Q92918 | 2/20 | 0.36 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | TYK2 | P29597 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | HTR5A | P47898 | 1/20 | 0.31 |
| ▸ | AURKA | O14965 | 1/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.31 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.31 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25815974 | 0.76 | KDM4E (0.33) | KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL25815758 | 0.75 | MAP4K1 (0.33) | MAP4K1ABL1GRM5HTR5AAURKA | |
| SCHEMBL15464515 | 0.74 | TRPV3 (0.39) | TRPV3IRAK4CD274 | |
| SCHEMBL24028061 | 0.69 | NPC1 (0.34) | MAP4K1TRPV3KDM4EALDH1A1PDCD1 | |
| SCHEMBL30212751 | 0.69 | NPC1 (0.34) | MAP4K1TRPV3KDM4EALDH1A1PDCD1 | |
| SCHEMBL25815755 | 0.66 | — | — | |
| SCHEMBL15282441 | 0.65 | ALDH1A1 (0.42) | KDM4EALDH1A1KMT2A | |
| SCHEMBL12371974 | 0.65 | MAP4K1 (0.44) | MAP4K1ACHE | |
| SCHEMBL13531369 | 0.64 | MAP4K4 (0.43) | KDM4EALDH1A1GRM5FGFR1MEN1 | |
| SCHEMBL18640651 | 0.63 | KDM4E (0.61) | TRPV3KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125182-A1 | PROPIONIC ACID DERIVATIVE AND MEDICAL USE THEREOF | 海思科医药集团股份有限公司 | 2023-07-06 | — | — | WO | disclosed |