Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K1 | Q92918 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | HTR5A | P47898 | 1/20 | 0.31 |
| ▸ | AURKA | O14965 | 1/20 | 0.31 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.31 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.30 |
| ▸ | FEN1 | P39748 | 1/20 | 0.30 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25815754 | 0.75 | MAP4K1 (0.36) | MAP4K1ABL1GRM5HTR5AAURKA | |
| SCHEMBL3924094 | 0.66 | NOS3 (0.41) | ACHEPDK2 | |
| SCHEMBL12371974 | 0.65 | MAP4K1 (0.44) | MAP4K1GAAMGAMSIMGAM2 | |
| SCHEMBL13531369 | 0.64 | MAP4K4 (0.43) | NPC1RAB9ASMN1; SMN2GRM5FGFR1 | |
| SCHEMBL4499172 | 0.62 | NNMT (0.46) | SMN1; SMN2GRM5 | |
| SCHEMBL14886180 | 0.61 | ACHE (0.44) | GAANPC1RAB9ASMN1; SMN2ABL1 | |
| SCHEMBL23370223 | 0.61 | USP1 (0.31) | — | |
| SCHEMBL12578985 | 0.61 | NOS3 (0.52) | NPC1RAB9AGRM5ACHEPDK2 | |
| SCHEMBL18939806 | 0.60 | ACHE (0.48) | GAANPC1RAB9ASMN1; SMN2HTR5A | |
| SCHEMBL18938791 | 0.60 | CYP2A6 (0.43) | NPC1RAB9ASMN1; SMN2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125182-A1 | PROPIONIC ACID DERIVATIVE AND MEDICAL USE THEREOF | 海思科医药集团股份有限公司 | 2023-07-06 | — | — | WO | disclosed |