SCHEMBL2581780

SCHEMBL2581780

NC(=S)c1ccc(F)c(F)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 2/20 0.54
CES1 P23141 2/20 0.54
PRKCI P41743 1/20 0.41
HTT P42858 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
PLA2G7 Q13093 1/20 0.40
RAB9A P51151 1/20 0.39
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
CYP1A2 P05177 1/20 0.37
POLB P06746 1/20 0.37
CHRNA1 P02708 1/20 0.37
CHRNG P07510 1/20 0.37
CHRNB1 P11230 1/20 0.37
CHRNB2 P17787 1/20 0.37
SLC6A2 P23975 1/20 0.37
CHRNB4 P30926 1/20 0.37
CHRNA3 P32297 1/20 0.37
CHRNA4 P43681 1/20 0.37
SLC6A3 Q01959 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29484322 1.00 CES2 (0.54) CES2CES1PRKCIHTTSMN1; SMN2
SCHEMBL18003362 0.80 CTSL (0.50) CES2CES1PRKCIHTTSMN1; SMN2
SCHEMBL3374366 0.80 HTT (0.48) PRKCIHTTSMN1; SMN2RAB9AMEN1
SCHEMBL7846469 0.80 KCNQ3 (0.41) CES2CES1PRKCIHTTSMN1; SMN2
SCHEMBL9585198 0.78 CES2 (0.56) CES2CES1HTTPLA2G7RAB9A
SCHEMBL16527165 0.77 PTPN7 (0.47) PRKCIVNN1KCNQ3KCNQ2
SCHEMBL4822867 0.77 KIF11 (0.47) PRKCIKCNQ3KCNQ2
SCHEMBL24490051 0.76 CES2 (0.54) CES2CES1PLA2G7RAB9AMEN1
SCHEMBL1262883 0.76 CES2 (0.54) CES2CES1LMNA
SCHEMBL20938010 0.76 CES2 (0.54) CES2CES1PLA2G7RAB9AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260103775-A1 PROCESS FOR LEACHING METAL SULFIDES WITH REAGENTS HAVING THIOCARBONYL FUNCTIONAL GROUPS JETTI RESOURCES, LLC (US) 2026-04-16 US claimed
US-12416066-B2 Process for leaching metal sulfides with reagents having thiocarbonyl functional groups JETTI RESOURCES, LLC (US) 2025-09-16 US claimed
US-20250092487-A1 METHODS FOR LIBERATING PRECIOUS METALS USING A REAGENT HAVING A THIOCARBONYL FUNCTIONAL GROUP JETTI RESOURCES, LLC (US) 2025-03-20 US claimed
EP-4461833-A1 PROCESS FOR LEACHING METAL SULFIDES WITH REAGENTS HAVING THIOCARBONYL FUNCTIONAL GROUPS Jetti Resources, LLC (US) 2024-11-13 EP claimed
US-20240336991-A1 PROCESS FOR LEACHING METAL SULFIDES WITH REAGENTS HAVING THIOCARBONYL FUNCTIONAL GROUPS JETTI RESOURCES, LLC (US) 2024-10-10 US claimed
US-12049681-B2 Process for leaching metal sulfides with reagents having thiocarbonyl functional groups JETTI RESOURCES, LLC (US) 2024-07-30 US claimed
EP-3283661-B1 PROCESS FOR LEACHING METAL SULFIDES WITH REAGENTS HAVING THIOCARBONYL FUNCTIONAL GROUPS JETTI RESOURCES LLC (US) 2024-06-05 EP claimed
US-20240167121-A1 PROCESS FOR LEACHING METAL SULFIDES WITH REAGENTS HAVING THIOCARBONYL FUNCTIONAL GROUPS JETTI RESOURCES, LLC (US) 2024-05-23 US claimed
US-11859263-B2 Process for leaching metal sulfides with reagents having thiocarbonyl functional groups JETTI RESOURCES, LLC (US) 2024-01-02 US claimed
WO-2022245731-A1 METHODS FOR LIBERATING PRECIOUS METALS USING A REAGENT HAVING A THIOCARBONYL FUNCTIONAL GROUP JETTI RESOURCES, LLC (US) 2022-11-24 WO claimed
CN-107532229-B Process for leaching metal sulphides with an agent having a thiocarbonyl function 不列颠哥伦比亚大学 2021-10-08 CN claimed
US-10961604-B2 Process for leaching metal sulfides with reagents having thiocarbonyl functional groups THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2021-03-30 US claimed
US-10954583-B2 Process for leaching metal sulfides with reagents having thiocarbonyl functional groups THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2021-03-23 US claimed
US-20200181737-A1 Process for Leaching Metal Sulfides with Reagents Having Thiocarbonyl Functional Groups JETTI RESOURCES, LLC 2020-06-11 US claimed
US-20200149131-A1 Process for Leaching Metal Sulfides with Reagents Having Thiocarbonyl Functional Groups JETTI RESOURCES, LLC 2020-05-14 US claimed
US-20200048736-A1 PROCESS FOR LEACHING METAL SULFIDES WITH REAGENTS HAVING THIOCARBONYL FUNCTIONAL GROUPS JETTI RESOURCES, LLC 2020-02-13 US claimed
EP-4214343-B1 EXTRACTING BASE METALS USING A WETTING AGENT AND A THIOCARBONYL FUNCTIONAL GROUP REAGENT JETTI RESOURCES LLC (US) 2026-05-06 EP disclosed
US-20260103775-A1 PROCESS FOR LEACHING METAL SULFIDES WITH REAGENTS HAVING THIOCARBONYL FUNCTIONAL GROUPS JETTI RESOURCES, LLC (US) 2026-04-16 US disclosed
WO-2008076562-A1 5- [4- (AZETIDIN-3-YL0XY) -PHENYL] -2-PHENYL-5H-THIAZ0L0 [5,4-C] PYRIDIN-4-0NE DERIVATIVES AND THEIR USE AS MCH RECEPTOR ANTAGONISTS ELI LILLY AND COMPANY (US) 2008-06-26 WO disclosed
WO-2004058254-A1 HETEROARYLALKANOIC ACIDS AS INTEGRIN RECEPTOR ANTAGONISTS PHARMACIA CORPORATION (US) 2004-07-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260103775-A1 PROCESS FOR LEACHING METAL SULFIDES WITH REAGENTS HAVING THIOCARBONYL FUNCTIONAL GROUPS TST, FECH, SLC6A12 CES2 915/4885CES1 2988/4885PRKCI 2399/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.