Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 1/20 | 0.44 |
| ▸ | MGAM | O43451 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SI | P14410 | 1/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | CAD | P27708 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12160531 | 0.92 | TGFBR1 (0.42) | TGFBR1MGAMGAASIMGAM2 | |
| SCHEMBL5490987 | 0.82 | TGFBR1 (0.43) | TGFBR1MGAMGAASIMGAM2 | |
| SCHEMBL12160526 | 0.81 | EGLN1 (0.38) | TGFBR1MGAMGAASIMGAM2 | |
| Methacrylic Acid SCHEMBL27674399 | 0.81 | LMNA (0.46) | TGFBR1MGAMGAASIMGAM2 | |
| SCHEMBL1332017 | 0.79 | LMNA (0.53) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL81193 | 0.79 | LMNA (0.53) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL1330728 | 0.79 | LMNA (0.53) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL1332187 | 0.79 | LMNA (0.53) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL1331748 | 0.79 | LMNA (0.53) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL3787404 | 0.77 | LMNA (0.51) | MGAMGAASIMGAM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011146408-A1 | HPMA POLYMER PLATINUM CHELATES | ACCESS PHARMACEUTICALS, INC. (US) | 2011-11-24 | — | — | WO | disclosed |
| WO-2011146408-A1 | HPMA POLYMER PLATINUM CHELATES | ACCESS PHARMACEUTICALS, INC. (US) | 2011-11-24 | — | — | WO | disclosed |
| US-20110286958-A1 | HPMA POLYMER PLATINUM CHELATES | ACCESS PHARMACEUTICALS, INC. | 2011-11-24 | — | — | US | disclosed |
| US-7754684-B2 | Macromolecular platinum chelates | ACCESS PHARMACEUTICALS, INC. (US) | 2010-07-13 | — | — | US | disclosed |
| US-7754684-B2 | Macromolecular platinum chelates | ACCESS PHARMACEUTICALS, INC. (US) | 2010-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110286958-A1 | HPMA POLYMER PLATINUM CHELATES | SLC46A1, PBRM1, SLC40A1 | TGFBR1 2782/4885MGAM 1930/4885GAA 2560/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.