Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.50 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | FDPS | P14324 | 1/20 | 0.43 |
| ▸ | CBLB | Q13191 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | RAF1 | P04049 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10263164 | 0.85 | BRAF (0.47) | KDM4CNPC1RAB9APARP1TSHR | |
| SCHEMBL8486170 | 0.81 | CTSA (0.54) | KDM4CANO1NPC1RAB9APARP1 | |
| SCHEMBL179291 | 0.81 | ALDH1A1 (0.48) | KDM4CNPC1RAB9APARP1CBLB | |
| SCHEMBL161556 | 0.81 | KDM4C (0.51) | KDM4CANO1NPC1RAB9APARP1 | |
| SCHEMBL25982936 | 0.81 | PARP1 (0.43) | KDM4CNPC1RAB9APARP1CBLB | |
| SCHEMBL178048 | 0.80 | KDM4C (0.75) | KDM4CANO1NPC1RAB9APARP1 | |
| SCHEMBL23015733 | 0.80 | RAB9A (0.47) | KDM4CNPC1RAB9ACBLBSMN1; SMN2 | |
| SCHEMBL25847358 | 0.80 | CBLB (0.43) | KDM4CNPC1RAB9ACBLBSMN1; SMN2 | |
| SCHEMBL25692508 | 0.79 | HPGD (0.46) | NPC1RAB9ACBLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL6169475 | 0.79 | ALDH1A1 (0.47) | KDM4CNPC1RAB9ACBLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219927-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219927-A1 | AKT3 MODULATORS | AKT3, AKT2, PIK3CA | KDM4C 4573/4885ANO1 3495/4885NPC1 901/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.