Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBLB | Q13191 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | BRAF | P15056 | 5/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | RAF1 | P04049 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10263164 | 0.81 | BRAF (0.47) | CBLBKDM4CNPC1RAB9APOLB | |
| SCHEMBL25820328 | 0.80 | KDM4C (0.50) | CBLBKDM4CNPC1RAB9ARECQL | |
| SCHEMBL25692506 | 0.78 | SMYD3 (0.55) | NPC1RAB9ASMN1; SMN2SMYD3 | |
| SCHEMBL25982936 | 0.77 | PARP1 (0.43) | CBLBKDM4CNPC1RAB9APOLB | |
| SCHEMBL23015733 | 0.76 | RAB9A (0.47) | CBLBKDM4CNPC1RAB9ABRAF | |
| SCHEMBL6169475 | 0.75 | ALDH1A1 (0.47) | CBLBKDM4CNPC1RAB9APOLB | |
| SCHEMBL101547 | 0.75 | KDM4E (0.55) | CBLBKDM4CNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13058657 | 0.75 | SMN1; SMN2 (0.58) | CBLBNPC1RAB9APOLBPKM | |
| SCHEMBL12017654 | 0.75 | ROCK2 (0.50) | CBLBNPC1RAB9APOLBSMN1; SMN2 | |
| SCHEMBL179291 | 0.74 | ALDH1A1 (0.48) | CBLBKDM4CNPC1RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219927-A1 | AKT3 MODULATORS | Georgiamune Inc. | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219927-A1 | AKT3 MODULATORS | AKT3, AKT2, PIK3CA | CBLB 3851/4885KDM4C 4573/4885NPC1 901/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.