Sugi Predict

Sugi Predict / Compounds / SCHEMBL6169475

SCHEMBL6169475

SCHEMBL6169475

CC(=O)c1cc(C(C)C)ccn1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 5/20 0.47
▸ CBLB Q13191 1/20 0.39
▸ KDM4C Q9H3R0 2/20 0.37
▸ KDM4E B2RXH2 4/20 0.37
▸ MAPT P10636 2/20 0.37
▸ KDM6B O15054 1/20 0.37
▸ TET3 O43151 1/20 0.37
▸ KDM4A O75164 1/20 0.37
▸ BBOX1 O75936 1/20 0.37
▸ KDM5A P29375 1/20 0.37
▸ KDM5C P41229 1/20 0.37
▸ ASPH Q12797 1/20 0.37
▸ KDM4D Q6B0I6 1/20 0.37
▸ TET2 Q6N021 1/20 0.37
▸ ALKBH5 Q6P6C2 1/20 0.37
▸ KDM7A Q6ZMT4 1/20 0.37
▸ KDM8 Q8N371 1/20 0.37
▸ TET1 Q8NFU7 1/20 0.37
▸ EGLN2 Q96KS0 1/20 0.37
▸ FTO Q9C0B1 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL101547 0.85 KDM4E (0.55) ALDH1A1CBLBKDM4CKDM4EMAPT
SCHEMBL10204249 0.83 RAF1 (0.43) ALDH1A1CBLBKDM4CKDM4EMAPT
SCHEMBL18542887 0.83 KDM4C (0.40) ALDH1A1CBLBKDM4CKDM4EMAPT
SCHEMBL9298319 0.81 ALDH1A1 (0.44) ALDH1A1KDM4CKDM4EMAPTKDM6B
SCHEMBL179291 0.80 ALDH1A1 (0.48) ALDH1A1CBLBKDM4CKDM4EMAPT
SCHEMBL10263164 0.80 BRAF (0.47) ALDH1A1CBLBKDM4CKDM4EMAPT
SCHEMBL12015752 0.80 ALDH1A1 (0.41) ALDH1A1CBLBKDM4CKDM4EMAPT
SCHEMBL18874516 0.79 TRPA1 (0.37) ALDH1A1CBLBKDM4CKDM4EMAPT
SCHEMBL19866406 0.79 KDM4C (0.33) ALDH1A1CBLBKDM4CKDM4EMAPT
SCHEMBL6171579 0.79 CBLB (0.36) ALDH1A1CBLBKDM4CKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11504443-B2 Odor-modulating agent and odor-modulating method YAMAMOTO PERFUMERY CO., LTD. (JP) 2022-11-22 — — US claimed
CN-111565764-A Odor conversion agent for conversion of odor of asphalt, sludge, sewage, ginkgo biloba, compost, marine animal, vegetable, garbage or coating, and odor conversion method for conversion of odor of asphalt, sludge, sewage, ginkgo biloba, compost, marine animal, vegetable, garbage or coating 山本香料株式会社 2020-08-21 — — CN claimed
US-20190175777-A1 ODOR-MODULATING AGENT AND ODOR-MODULATING METHOD YAMAMOTO PERFUMERY CO., LTD. (JP) 2019-06-13 — — US claimed
EP-3467078-A1 ODOR-MODULATING AGENT AND ODOR-MODULATING METHOD Yamamoto Perfumery Co. Ltd. (JP) 2019-04-10 — — EP claimed
US-20240108040-A1 HIGH INTENSITY SWEETENERS FIRMENICH INCORPORATED (US) 2024-04-04 — — US disclosed
US-11758933-B2 High intensity sweeteners FIRMENICH INCORPORATED (US) 2023-09-19 — — US disclosed
US-20230138480-A1 COMPOUNDS AND USES THEREOF FOGHORN THERAPEUTICS INC. 2023-05-04 — — US disclosed
US-11504443-B2 Odor-modulating agent and odor-modulating method YAMAMOTO PERFUMERY CO., LTD. (JP) 2022-11-22 — — US disclosed
CN-114672359-A Lubricating oil 山本香料株式会社 2022-06-28 — — CN disclosed
EP-3368542-B1 HIGH INTENSITY SWEETENERS FIRMENICH INCORPORATED (US) 2022-06-22 — — EP disclosed
US-11357246-B2 High intensity sweeteners FIRMENICH INCORPORATED (US) 2022-06-14 — — US disclosed
US-20210227863-A1 HIGH INTENSITY SWEETENERS SENOMYX, INC. 2021-07-29 — — US disclosed
WO-2012101013-A1 SUBSTITUTED PYRIDINYL-PYRIMIDINES AND THEIR USE AS MEDICAMENTS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2012-08-02 — — WO disclosed
US-20100010001-A1 NOVEL MODULATORS OF SPHINGOSINE PHOSPHATE RECEPTORS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2010-01-14 — — US disclosed
EP-1045833-B1 2,3-SUBSTITUTED INDOLE COMPOUNDS AS COX-2 INHIBITORS PFIZER (US) 2005-11-02 — — EP disclosed
US-6608070-B1 Useful for treatment of medical condition in which prostaglandins are implicated as pathogens NAKAO KAZUNARI (JP) 2003-08-19 — — US disclosed
CN-1284064-A 2,3-substituted indole compounds as cox-2 inhibitors PFIZER PHARMA (US) 2001-02-14 — — CN disclosed
EP-1045833-A1 2,3-SUBSTITUTED INDOLE COMPOUNDS AS COX-2 INHIBITORS PFIZER INC. (US) 2000-10-25 — — EP disclosed
WO-1999035130-A1 2,3-SUBSTITUTED INDOLE COMPOUNDS AS COX-2 INHIBITORS PFIZER PHARMACEUTICALS INC. (JP) 1999-07-15 — — WO disclosed
US-5214027-A For use with synthetic peppermint essential oil in foods and cosmetics SHIONO KORYO KAISHA, LTD. (JP) 1993-05-25 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240108040-A1 HIGH INTENSITY SWEETENERS TAS2R40, TAS2R60, TAS1R1 ALDH1A1 978/4885CBLB 4873/4885KDM4C 4179/4885
US-20230138480-A1 COMPOUNDS AND USES THEREOF VHL, CLN6, TFEB ALDH1A1 2571/4885CBLB 1564/4885KDM4C 1962/4885
US-11357246-B2 High intensity sweeteners TAS2R40, TAS2R60, TAS1R1 ALDH1A1 978/4885CBLB 4873/4885KDM4C 4179/4885
US-20210227863-A1 HIGH INTENSITY SWEETENERS TAS2R40, TAS2R60, TAS1R1 ALDH1A1 978/4885CBLB 4873/4885KDM4C 4179/4885
US-11758933-B2 High intensity sweeteners TAS2R40, TAS2R60, TAS1R1 ALDH1A1 978/4885CBLB 4873/4885KDM4C 4179/4885
US-20100010001-A1 NOVEL MODULATORS OF SPHINGOSINE PHOSPHATE RECEPTORS S1PR1, S1PR3, S1PR4 ALDH1A1 3074/4885CBLB 4743/4885KDM4C 3411/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.