SCHEMBL161556

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL164646	0.84	ANO1 (0.51)	KDM4CANO1NPC1RAB9APARP1
	SCHEMBL8486170	0.83	CTSA (0.54)	KDM4CANO1NPC1RAB9ATSHR
	SCHEMBL163711	0.82	KDR (0.48)	KDM4CNPC1RAB9ATSHRPARP1
	SCHEMBL178048	0.81	KDM4C (0.75)	KDM4CANO1NPC1RAB9ATSHR
	SCHEMBL25820328	0.81	KDM4C (0.50)	KDM4CANO1NPC1RAB9ATSHR
	SCHEMBL162598	0.80	RAB9A (0.50)	KDM4CNPC1RAB9ATSHRSMN1; SMN2
	SCHEMBL25832636	0.79	CTSA (0.57)	KDM4CANO1NPC1RAB9ATSHR
	SCHEMBL19249060	0.78	GRM5 (0.50)	KDM4CANO1NPC1RAB9ATSHR
	SCHEMBL163424	0.77	ALDH1A1 (0.51)	KDM4CPARP1ALDH1A1HPGDKDM4E
	SCHEMBL162424	0.76	PARP1 (0.45)	NPC1RAB9APARP1HTTCNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.