Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2547787 | 0.84 | CHRM5 (0.39) | ACHEHPGDKMT2ASMN1; SMN2HTR6 | |
| SCHEMBL25815809 | 0.81 | HTR6 (0.40) | ACHEHPGDKMT2ASMN1; SMN2HTR6 | |
| SCHEMBL25027129 | 0.80 | ACHE (0.53) | ACHEPOLBOPRM1OPRD1OPRK1 | |
| SCHEMBL25815386 | 0.80 | SMN1; SMN2 (0.34) | ACHEHPGDKMT2ASMN1; SMN2HTR6 | |
| SCHEMBL24480842 | 0.80 | KMT2A (0.40) | ACHEHPGDKMT2ASMN1; SMN2HTR6 | |
| SCHEMBL24802118 | 0.78 | ACHE (0.38) | ACHEPOLB | |
| SCHEMBL27051153 | 0.78 | ACHE (0.35) | ACHE | |
| SCHEMBL24480965 | 0.75 | KMT2A (0.39) | ACHEKMT2APOLBOPRM1OPRD1 | |
| SCHEMBL15499056 | 0.75 | ACHE (0.41) | ACHESMN1; SMN2POLB | |
| SCHEMBL24480218 | 0.75 | ACHE (0.50) | ACHEKMT2APOLBOPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125944-A1 | COMPOUND CONTAINING HETEROCYCLIC RING | 正大天晴药业集团股份有限公司 | 2023-07-06 | — | — | WO | disclosed |