Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | GNAO1 | P09471 | 4/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GNAI3 | P08754 | 3/20 | 0.31 |
| ▸ | GNAI1 | P63096 | 3/20 | 0.31 |
| ▸ | CCR5 | P51681 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.31 |
| ▸ | GBA1 | P04062 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24480854 | 0.92 | HTR6 (0.33) | SMN1; SMN2HPGDKMT2AHTR6GNAO1 | |
| SCHEMBL24319470 | 0.87 | KDM4E (0.34) | ACHEGNAO1GNAI3GNAI1OPRM1 | |
| SCHEMBL24480419 | 0.86 | TACR1 (0.32) | HTR6GBA1 | |
| SCHEMBL24480857 | 0.84 | ACHE (0.40) | SMN1; SMN2ACHEGNAO1POLBGNAI3 | |
| SCHEMBL2547787 | 0.84 | CHRM5 (0.39) | SMN1; SMN2HPGDKMT2AACHEHTR6 | |
| SCHEMBL19782068 | 0.84 | POLB (0.38) | SMN1; SMN2ACHEGNAO1POLBGBA1 | |
| SCHEMBL24480879 | 0.83 | KDM1A (0.37) | SMN1; SMN2ACHEPOLBGBA1 | |
| SCHEMBL24319406 | 0.81 | ALDH1A1 (0.37) | ACHEPOLBOPRM1OPRD1OPRK1 | |
| SCHEMBL25815809 | 0.81 | HTR6 (0.40) | SMN1; SMN2HPGDKMT2AACHEHTR6 | |
| SCHEMBL25027122 | 0.80 | NCF1 (0.37) | SMN1; SMN2HPGDKMT2AACHEGNAO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125944-A1 | COMPOUND CONTAINING HETEROCYCLIC RING | 正大天晴药业集团股份有限公司 | 2023-07-06 | — | — | WO | disclosed |