SCHEMBL25823469

SCHEMBL25823469

C=C(CCC)C(=O)Oc1ccccc1-c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 10/20 0.45
ALDH1A1 P00352 6/20 0.44
L3MBTL1 Q9Y468 4/20 0.44
SMN1; SMN2 Q16637 3/20 0.44
TDP1 Q9NUW8 3/20 0.44
FABP3 P05413 2/20 0.43
FABP7 O15540 1/20 0.43
FABP5 Q01469 1/20 0.43
LMNA P02545 3/20 0.43
MAPK1 P28482 2/20 0.43
HPGD P15428 1/20 0.41
RXRA P19793 1/20 0.41
RXRB P28702 1/20 0.41
RXRG P48443 1/20 0.41
KMT2A Q03164 4/20 0.41
HTT P42858 1/20 0.41
PKM P14618 1/20 0.41
MEN1 O00255 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9985386 0.88 L3MBTL1 (0.46) KDM4EALDH1A1L3MBTL1SMN1; SMN2TDP1
SCHEMBL426386 0.88 TDP1 (0.46) KDM4EALDH1A1L3MBTL1SMN1; SMN2TDP1
SCHEMBL29117762 0.83 L3MBTL1 (0.42) KDM4EALDH1A1L3MBTL1SMN1; SMN2TDP1
SCHEMBL2390126 0.83 KDM4E (0.53) KDM4EALDH1A1L3MBTL1SMN1; SMN2TDP1
SCHEMBL34470443 0.83 KDM4E (0.53) KDM4EALDH1A1L3MBTL1SMN1; SMN2TDP1
SCHEMBL28487364 0.80 FABP3 (0.56) KDM4EALDH1A1L3MBTL1SMN1; SMN2TDP1
SCHEMBL28008688 0.80 THRA (0.44) KDM4EL3MBTL1TDP1HPGDKMT2A
SCHEMBL17352103 0.80 MTNR1B (0.47) KDM4EALDH1A1L3MBTL1SMN1; SMN2LMNA
SCHEMBL1949303 0.80 GAA (0.43) KDM4ESMN1; SMN2TDP1LMNAKMT2A
SCHEMBL242193 0.79 ELANE (0.50) KDM4EALDH1A1L3MBTL1SMN1; SMN2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230212136-A1 CURABLE RESIN COMPOSITION, CURED PRODUCT, DIFFRACTIVE OPTICAL ELEMENT, AND MULTILAYER DIFFRACTIVE OPTICAL ELEMENT FUJIFILM CORPORATION (JP) 2023-07-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230212136-A1 CURABLE RESIN COMPOSITION, CURED PRODUCT, DIFFRACTIVE OPTICAL ELEMENT, AND MULTILAYER DIFFRACTIVE OPTICAL ELEMENT TERB1, RER1, LARP1 KDM4E 1968/4885ALDH1A1 228/4885L3MBTL1 2710/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.