Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | AOC1 | P19801 | 1/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | ITK | Q08881 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3130734 | 0.90 | TSHR (0.41) | TSHRKMT2AEPHX1EPHX2HAO1 | |
| SCHEMBL15576247 | 0.84 | TSHR (0.41) | TSHRKMT2AEPHX1EPHX2HAO1 | |
| SCHEMBL2208539 | 0.74 | CHRNB4 (0.48) | — | |
| SCHEMBL21799837 | 0.74 | APP (0.44) | KMT2AEPHX1EPHX2PTPN1RXFP1 | |
| SCHEMBL29922690 | 0.74 | APP (0.44) | KMT2AEPHX1EPHX2PTPN1RXFP1 | |
| SCHEMBL13379511 | 0.74 | DDB1 (0.43) | EPHX1EPHX2PTPN1RXFP1AOC1 | |
| SCHEMBL2151303 | 0.73 | MEN1 (0.47) | KMT2AEPHX1EPHX2PTPN1RXFP1 | |
| SCHEMBL12204104 | 0.73 | MEN1 (0.44) | KMT2AEPHX1EPHX2PTPN1RXFP1 | |
| SCHEMBL2150885 | 0.72 | HTR6 (0.45) | EPHX1EPHX2PTPN1RXFP1AOC1 | |
| SCHEMBL3128015 | 0.72 | ALDH1A1 (0.43) | KMT2AEPHX1EPHX2PTPN1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230218549-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ACUCELA INC. | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230218549-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ALDH1A2, CLN6, AGER | TSHR 2971/4885KMT2A 3008/4885EPHX1 1150/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.