SCHEMBL258244

SCHEMBL258244

CC(C)(c1ccc(Oc2ccccc2-c2ccc(C(=O)O)cc2)cc1)c1ccc(Oc2ccccc2-c2ccc(C(=O)O)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
FEN1 P39748 2/20 0.50
CAMKK2 Q96RR4 1/20 0.50
FFAR4 Q5NUL3 1/20 0.49
PTGS2 P35354 1/20 0.48
RXRA P19793 1/20 0.47
RXRB P28702 1/20 0.47
RXRG P48443 1/20 0.47
NCOA1 Q15788 1/20 0.47
NCOA3 Q9Y6Q9 1/20 0.47
SRD5A2 P31213 2/20 0.45
CASP1 P29466 1/20 0.44
BRD4 O60885 1/20 0.43
LPAR1 Q92633 3/20 0.43
LPAR5 Q9H1C0 3/20 0.43
TTR P02766 1/20 0.43
EGFR P00533 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30856503 0.89 FFAR4 (0.58) FEN1CAMKK2FFAR4PTGS2RXRA
SCHEMBL30856488 0.87 SRD5A2 (0.59) FEN1CAMKK2FFAR4PTGS2RXRA
SCHEMBL25343498 0.86 CYP2C8 (0.53) FEN1CAMKK2FFAR4PTGS2RXRA
SCHEMBL30519278 0.86 CYP2C8 (0.53) FEN1CAMKK2FFAR4PTGS2RXRA
SCHEMBL21178076 0.86 NCOA1 (0.58) FEN1CAMKK2FFAR4PTGS2RXRA
SCHEMBL4326298 0.85 NCOA1 (0.62) FEN1CAMKK2FFAR4PTGS2RXRA
SCHEMBL1634704 0.81 PARP15 (0.58) RXRARXRBRXRGSRD5A2
SCHEMBL9422294 0.81 SRD5A2 (0.61) FEN1CAMKK2RXRARXRBRXRG
SCHEMBL2710772 0.79 SRD5A2 (0.59) FEN1CAMKK2RXRARXRBRXRG
SCHEMBL25908089 0.77 PTGS2 (0.59) CAMKK2FFAR4PTGS2NCOA1NCOA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11434322-B2 Sulfobetaine group-comprising reactive compound, polymer thereof, and method of producing the polymer NAGASE CHEMTEX CORPORATION (JP) 2022-09-06 US disclosed
EP-3604275-B1 SULFOBETAINE-GROUP-CONTAINING REACTIVE COMPOUND, POLYMER THEREOF, AND METHOD FOR PRODUCING POLYMER NAGASE CHEMTEX CORP (JP) 2022-02-16 EP disclosed
US-20200131300-A1 SULFOBETAINE GROUP-CONTAINING REACTIVE COMPOUND, POLYMER THEREOF, AND METHOD FOR PRODUCING POLYMER NAGASE CHEMTEX CORPORATION (JP) 2020-04-30 US disclosed
EP-3604275-A1 SULFOBETAINE-GROUP-CONTAINING REACTIVE COMPOUND, POLYMER THEREOF, AND METHOD FOR PRODUCING POLYMER Nagase ChemteX Corporation (JP) 2020-02-05 EP disclosed
EP-2058353-B1 DIAMINE COMPOUND HAVING PHOSPHORYLCHOLINE GROUP, POLYMER THEREOF AND METHOD FOR PRODUCING THE SAME UNIV TOKAI EDUCATIONAL SYSTEM (JP) 2012-02-15 EP disclosed
US-8063238-B2 Diamine compound having phosphorylcholine group, polymer thereof, and process for producing the polymer TOKAI UNIVERSITY EDUCATIONAL SYSTEM (JP) 2011-11-22 US disclosed
US-20100036081-A1 Diamine Compound Having Phosphorylcholine Group, Polymer Thereof, and Process for Producing the Polymer TOKAI UNIVERSITY EDUCATIONAL SYSTEM (JP) 2010-02-11 US disclosed
EP-2058353-A1 DIAMINE COMPOUND HAVING PHOSPHORYLCHOLINE GROUP, POLYMER THEREOF AND METHOD FOR PRODUCING THE SAME TOKAI UNIVERSITY EDUCATIONAL SYSTEM (JP) 2009-05-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200131300-A1 SULFOBETAINE GROUP-CONTAINING REACTIVE COMPOUND, POLYMER THEREOF, AND METHOD FOR PRODUCING POLYMER CBR3, SCO2, MSRB3 FEN1 1533/4885CAMKK2 4634/4885FFAR4 1635/4885
US-20100036081-A1 Diamine Compound Having Phosphorylcholine Group, Polymer Thereof, and Process for Producing the Polymer PHOSPHO1, PCTP, PDAP1 FEN1 3629/4885CAMKK2 3117/4885FFAR4 4247/4885
US-11434322-B2 Sulfobetaine group-comprising reactive compound, polymer thereof, and method of producing the polymer CBR3, SCO2, MSRB3 FEN1 1844/4885CAMKK2 4589/4885FFAR4 1609/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.