Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 4/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | IKBKB | O14920 | 3/20 | 0.42 |
| ▸ | BRAF | P15056 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | TLR4 | O00206 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | TEK | Q02763 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4894524 | 0.83 | CYP1A2 (0.56) | CYP1A2CYP2C9CYP2C19GAAALDH1A1 | |
| SCHEMBL3056560 | 0.79 | CYP1A2 (0.53) | CYP1A2CYP2C9CYP2C19GAAALDH1A1 | |
| SCHEMBL20204806 | 0.77 | MAPT (0.47) | CYP1A2CYP2C9CYP2C19ALDH1A1MAPT | |
| SCHEMBL15822750 | 0.73 | DHFR (0.38) | GAALMNA | |
| SCHEMBL621401 | 0.73 | CYP1A2 (0.37) | CYP1A2CYP2C9CYP2C19IKBKBALDH1A1 | |
| SCHEMBL30879271 | 0.72 | TSHR (0.59) | ALDH1A1 | |
| SCHEMBL15814847 | 0.72 | TDP1 (0.47) | LTA4HGAAALDH1A1MAPTL3MBTL1 | |
| SCHEMBL621076 | 0.72 | CYP1A2 (0.36) | CYP1A2CYP2C9CYP2C19IKBKBGAA | |
| SCHEMBL31460934 | 0.72 | ALDH1A1 (0.66) | LTA4HCYP1A2CYP2C9CYP2C19IKBKB | |
| SCHEMBL8069572 | 0.72 | DUT (0.39) | CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122298-A1 | PROTEIN STABILIZING COMPOUNDS CONTAINING USP28 AND/OR USP25 TARGETING LIGANDS | Stablix, Inc. (US) | 2023-06-29 | — | — | WO | disclosed |