Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KARS1 | Q15046 | 1/20 | 0.36 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA3 | P07451 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25824613 | 0.87 | CYP1A2 (0.40) | CYP1A2CYP3A4CYP2D6MAPTCYP2C9 | |
| SCHEMBL25824658 | 0.80 | CYP3A4 (0.38) | CYP1A2CYP3A4CYP2D6MAPTCYP2C9 | |
| SCHEMBL25824667 | 0.80 | CYP3A4 (0.38) | CYP1A2CYP3A4CYP2D6MAPTCYP2C9 | |
| SCHEMBL21799640 | 0.79 | MAPT (0.44) | CYP1A2CYP3A4CYP2D6MAPTCYP2C9 | |
| SCHEMBL29922565 | 0.79 | MAPT (0.44) | CYP1A2CYP3A4CYP2D6MAPTCYP2C9 | |
| SCHEMBL3130507 | 0.78 | HTR6 (0.47) | CYP1A2CYP3A4CYP2D6MAPTCYP2C9 | |
| SCHEMBL21942318 | 0.77 | HDAC4 (0.34) | — | |
| SCHEMBL9480445 | 0.77 | MAPT (0.48) | CYP1A2CYP3A4CYP2D6MAPTCYP2C9 | |
| SCHEMBL2151126 | 0.76 | ADRB2 (0.40) | ALDH1A1TSHR | |
| SCHEMBL3138150 | 0.76 | AKR1C3 (0.41) | CA12CA9ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230218549-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ACUCELA INC. | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230218549-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ALDH1A2, CLN6, AGER | CYP1A2 2835/4885CYP3A4 3598/4885CYP2D6 3632/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.