Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KARS1 | Q15046 | 1/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.35 |
| ▸ | F2R | P25116 | 2/20 | 0.34 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25824636 | 0.87 | CYP1A2 (0.42) | CYP1A2CYP3A4CYP2D6MAPTCYP2C9 | |
| SCHEMBL25824669 | 0.81 | TSHR (0.36) | CYP1A2CYP3A4CYP2D6MAPTCYP2C9 | |
| SCHEMBL25824662 | 0.81 | TSHR (0.36) | CYP1A2CYP3A4CYP2D6MAPTCYP2C9 | |
| SCHEMBL3128383 | 0.80 | S1PR1 (0.50) | S1PR4S1PR1S1PR5 | |
| SCHEMBL2150930 | 0.79 | ADRB2 (0.39) | TSHR | |
| SCHEMBL2150483 | 0.77 | AKR1C3 (0.40) | MAPTTSHRHSD17B10S1PR4S1PR1 | |
| SCHEMBL25824641 | 0.77 | CYP1A2 (0.44) | CYP1A2CYP3A4CYP2D6MAPTCYP2C9 | |
| SCHEMBL22414327 | 0.76 | MAPT (0.46) | CYP1A2CYP3A4MAPTCYP2C9CYP2C19 | |
| SCHEMBL9480445 | 0.74 | MAPT (0.48) | CYP1A2CYP3A4CYP2D6MAPTCYP2C9 | |
| SCHEMBL15946012 | 0.74 | S1PR1 (0.53) | S1PR4S1PR1S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230218549-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ACUCELA INC. | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230218549-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ALDH1A2, CLN6, AGER | CYP1A2 2835/4885CYP3A4 3598/4885CYP2D6 3632/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.